{"id":"W142584360","doi":"10.1016/s0065-3101(23)00056-7","title":"Cancer and Epigenesis: A Developmental Perspective","year":2003,"lang":"en","type":"article","venue":"Advances in Pediatrics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Chromatin; Epigenetics; DNA methylation; Histone; Biology; Genetics; Epigenomics; Epigenesis; Genomic imprinting; Gene; Cell biology; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001069652,0.00008280724,0.00006866785,0.00004629169,0.00003836319,0.000007912801,0.00004280481,0.00006217198,0.000006900664],"category_scores_gemma":[0.0001446214,0.0000844261,0.00001597144,0.0001292266,0.00002961081,0.000008499919,0.00002403431,0.00004210325,0.000001368436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003317264,"about_ca_system_score_gemma":0.00007872994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001660522,"about_ca_topic_score_gemma":0.0001663618,"domain_scores_codex":[0.9994325,0.00002605669,0.0001106167,0.0002246334,0.00006845155,0.0001377358],"domain_scores_gemma":[0.9997945,0.00001429622,0.00003839745,0.00006488759,0.00004912876,0.0000387968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000554502,0.0001495776,0.9075165,0.00005448027,0.00001946901,0.000007708522,0.0005138795,0.001063228,0.05223002,0.006807027,0.0001049353,0.0314777],"study_design_scores_gemma":[0.002502868,0.000451871,0.04525282,0.00002051236,0.00006032778,0.00001241735,0.003318285,0.00003734185,0.3633344,0.017728,0.5660816,0.00119962],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8621652,0.1315838,0.001043338,0.00003071669,0.00015434,0.00008856475,0.000006205657,0.000003973473,0.004923855],"genre_scores_gemma":[0.9041304,0.09134126,0.004137469,0.00005320654,0.0001032543,0.00002645565,0.000005333471,0.00001056711,0.0001920542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8622637,"threshold_uncertainty_score":0.3442796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007245662005672244,"score_gpt":0.2832341139195756,"score_spread":0.2759884519139034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}