{"id":"W1427987602","doi":"10.3233/jad-2000-23-403","title":"Aß Immunoreactive Material Is Present in Several Intracellular Compartments in Transfected, Neuronally Differentiated, P19 Cells Expressing the Human Amyloid ß-Protein Precursor","year":2000,"lang":"en","type":"article","venue":"Journal of Alzheimer s Disease","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Medical Research Council","keywords":"Golgi apparatus; Endoplasmic reticulum; Cell biology; Amyloid precursor protein; Immunogold labelling; Immunocytochemistry; Intracellular; Endosome; Subcellular localization; LAMP1; Transfection; Biology; Chemistry; Molecular biology; Alzheimer's disease; Pathology; Cytoplasm; Biochemistry; Antibody; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002430815,0.000397057,0.0006488166,0.0002851614,0.000145235,0.0001290294,0.0003194923,0.00008800725,0.001955545],"category_scores_gemma":[0.0000113318,0.0002747362,0.0003706093,0.0002637577,0.0001848163,0.0004226656,0.00004973613,0.0006306287,0.00005179024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001418235,"about_ca_system_score_gemma":0.0003613086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001573718,"about_ca_topic_score_gemma":0.000006201247,"domain_scores_codex":[0.9965674,0.000511367,0.0009077952,0.000367267,0.0009947454,0.0006514183],"domain_scores_gemma":[0.9984358,0.00004947935,0.0002451321,0.0004116555,0.0001335779,0.0007243394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.1414742,0.07811915,0.2372551,0.0008678717,0.07949673,0.04921184,0.01060501,0.002059453,0.3565328,0.00007212758,0.007081889,0.03722374],"study_design_scores_gemma":[0.01581291,0.0009072708,0.8948225,0.0009870493,0.003363587,0.00008013082,0.0001380292,0.0006325304,0.08212173,0.0003266418,0.0003530736,0.0004544878],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900129,0.007438032,0.000002988645,0.0007173999,0.0001146375,0.001374516,0.0001475056,0.00001637109,0.0001756025],"genre_scores_gemma":[0.9991269,0.0002244862,0.00004647543,0.0001274866,0.0002177025,0.0000670099,0.0000800769,0.00005389093,0.00005595319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6575674,"threshold_uncertainty_score":0.9999705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02302017929389158,"score_gpt":0.2903078701665175,"score_spread":0.2672876908726259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}