{"id":"W143619609","doi":"10.1023/a:1020705210855","title":"Genetic Selection for Modulators of the MAP Kinase and β-Catenin Growth-Control Pathways in Mammalian Cells","year":2002,"lang":"en","type":"article","venue":"Biochemical Genetics","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Aptose Biosciences (Canada)","funders":"","keywords":"Biology; Genetic screen; Kinase; Mitogen-activated protein kinase; Cell biology; Phenotype; Protein kinase A; Signal transduction; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002973293,0.000534284,0.0003382586,0.0005845978,0.0003178435,0.0005065246,0.0006062462,0.0004775577,0.00206695],"category_scores_gemma":[0.0003154074,0.0004639407,0.000366896,0.000410046,0.0003833943,0.0002178971,0.0004715066,0.0009232343,0.0006138386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005892512,"about_ca_system_score_gemma":0.0004360145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001054252,"about_ca_topic_score_gemma":0.002775428,"domain_scores_codex":[0.9997053,0.0000583402,0.00003423633,0.00005442045,0.00009691867,0.00005083604],"domain_scores_gemma":[0.9996257,0.0001157407,0.0001027024,0.00005170408,0.00002379414,0.00008032109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004353153,0.00001004219,0.00005088478,0.000006236945,0.000002551881,0.00003144556,0.000006433669,0.00004542157,0.9992428,0.0002533515,0.00001362368,0.0002937456],"study_design_scores_gemma":[0.00002683196,0.00006293521,0.0009301658,0.000002511236,0.0000184247,0.0001768691,0.00001892666,0.0007161315,0.9956969,0.00007003644,0.002275162,0.000005168856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815403,0.0008502582,0.01254802,0.0003522742,0.00009895554,0.0001406895,0.0005029122,0.0002911237,0.003675489],"genre_scores_gemma":[0.982113,0.000974391,0.009455387,0.0001779097,0.00002815867,0.0001184255,0.0006348524,0.0002262821,0.006271496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00206695,"threshold_uncertainty_score":0.006914616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00985745415457887,"score_gpt":0.1874815457356444,"score_spread":0.1776240915810656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}