{"id":"W143619609","doi":"10.1023/a:1020705210855","title":"Genetic Selection for Modulators of the MAP Kinase and β-Catenin Growth-Control Pathways in Mammalian Cells","year":2002,"lang":"en","type":"article","venue":"Biochemical Genetics","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Aptose Biosciences (Canada)","funders":"","keywords":"Biology; Genetic screen; Kinase; Mitogen-activated protein kinase; Cell biology; Phenotype; Protein kinase A; Signal transduction; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008116975,0.0001702303,0.0001639155,0.00003931417,0.00004249366,0.0000101804,0.0001865656,0.000236558,0.000008759289],"category_scores_gemma":[0.00004578342,0.0001428558,0.00009931954,0.0001051569,0.0001038292,0.000001462211,0.00007361946,0.00007327062,0.000002140326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000012378,"about_ca_system_score_gemma":0.00002035748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001297932,"about_ca_topic_score_gemma":0.000009233614,"domain_scores_codex":[0.9989548,0.00004351021,0.0002830007,0.0003445833,0.000107315,0.00026678],"domain_scores_gemma":[0.9994989,0.00001530485,0.00009193656,0.0002352112,0.00007262262,0.00008604188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002915521,0.00007119589,0.01269778,0.00006298254,0.00001337398,4.446721e-7,0.00003642186,0.00004403999,0.9846842,0.00003970339,0.00144889,0.0008718033],"study_design_scores_gemma":[0.0009934102,0.000201906,0.008990722,0.0000115137,0.00002197863,0.000006421268,0.00001361252,0.002638124,0.9849072,0.0002329988,0.001804236,0.0001779328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958178,0.002189588,0.001211469,0.00007862336,0.000154629,0.0004251175,0.00006667338,0.00000608443,0.00004998146],"genre_scores_gemma":[0.9966918,0.000135453,0.002697538,0.0001122635,0.0001711179,0.00004692752,0.00001298303,0.0000253544,0.0001065309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003707061,"threshold_uncertainty_score":0.5825489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00985745415457887,"score_gpt":0.1874815457356444,"score_spread":0.1776240915810656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}