{"id":"W1436852049","doi":"10.18632/oncotarget.4729","title":"SIRT1 in B[a]P-induced lung tumorigenesis","year":2015,"lang":"en","type":"article","venue":"Oncotarget","topic":"Sirtuins and Resveratrol in Medicine","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China; School of Medicine, New York University; York University; Zhejiang University; Sir Run Run Shaw Hospital","keywords":"Carcinogenesis; Lung cancer; Cancer research; Carcinogen; Lung; Benzo(a)pyrene; Medicine; Sirtuin 1; Chemistry; Biology; Cancer; Pathology; Internal medicine; Downregulation and upregulation; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002506335,0.0003874021,0.0002973911,0.0004678272,0.0003974284,0.00048948,0.0002241217,0.0005089796,0.003246488],"category_scores_gemma":[0.0001072928,0.0002398165,0.0006443866,0.0003053885,0.0003548502,0.0002785898,0.0003171128,0.0008250562,0.0009894157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003030745,"about_ca_system_score_gemma":0.0003085586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000785502,"about_ca_topic_score_gemma":0.0009666332,"domain_scores_codex":[0.9998643,0.00002188932,0.00001054849,0.00002658173,0.00003852552,0.00003817023],"domain_scores_gemma":[0.9998822,0.000006894417,0.00003671712,0.00001055078,0.00002049257,0.00004310835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002027635,0.0003040691,0.005181428,0.0004566238,0.00006806234,0.00065286,0.00008545173,0.0001782255,0.9743739,0.0006630014,0.001362613,0.01464614],"study_design_scores_gemma":[0.0004854565,0.002590018,0.1619841,0.0001337169,0.0003101169,0.002941323,0.0006206697,0.003961099,0.7771455,0.001152153,0.04861724,0.00005864311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9390339,0.04592402,0.004581833,0.001495598,0.0006023952,0.00009263155,0.001176744,0.0003410041,0.006751887],"genre_scores_gemma":[0.9814917,0.00986435,0.0007679986,0.0002546259,0.00007410064,0.00004125144,0.0007219951,0.00002035981,0.006763749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003246488,"threshold_uncertainty_score":0.01086056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04720969849470288,"score_gpt":0.3338097792573009,"score_spread":0.286600080762598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}