{"id":"W1440144999","doi":"10.1016/j.neurobiolaging.2015.08.029","title":"Suspected non-AD pathology in mild cognitive impairment","year":2015,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Janssen Research and Development; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Alzheimer's Disease Neuroimaging Initiative; GE Healthcare; National Institutes of Health; Genentech; Takeda Pharmaceutical Company; IXICO; Servier; Meso Scale Diagnostics; Johnson and Johnson; Eli Lilly and Company; U.S. Department of Defense; Novartis Pharmaceuticals Corporation; DoD Alzheimer's Disease Neuroimaging Initiative; Pfizer; Bristol-Myers Squibb; F. Hoffmann-La Roche; Roche; Alzheimer's Drug Discovery Foundation; Merck; National Institute on Aging; Fujirebio Europe; Alzheimer's Association","keywords":"Neurodegeneration; Dementia; Medicine; Hyperintensity; Alzheimer's disease; Cognition; Neuroimaging; Alzheimer's Disease Neuroimaging Initiative; Positron emission tomography; Snap; Cognitive decline; Amyloid (mycology); White matter; Internal medicine; Psychology; Hippocampus; Magnetic resonance imaging; Pathology; Neuroscience; Disease; Radiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001631293,0.001259475,0.0009567947,0.007065766,0.001981269,0.002036828,0.001359038,0.001645989,0.004590485],"category_scores_gemma":[0.00697278,0.0005997153,0.0006296313,0.001810987,0.001810671,0.001640011,0.001279328,0.0008481155,0.0009417676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000805573,"about_ca_system_score_gemma":0.001525605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005873463,"about_ca_topic_score_gemma":0.009144322,"domain_scores_codex":[0.9993581,0.0001297296,0.0001333743,0.00007697131,0.0001507786,0.0001509742],"domain_scores_gemma":[0.9974812,0.0006351508,0.0006895509,0.0001170443,0.0004361958,0.0006408916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003236691,0.0002288067,0.9580768,0.0003048893,0.00008689435,0.02711839,0.0005497675,0.0001682114,0.001833952,0.0002720549,0.000535179,0.007588256],"study_design_scores_gemma":[0.00008968204,0.001160292,0.9350679,0.000169995,0.0002270667,0.05733306,0.001243391,0.0009009128,0.001355588,0.001399692,0.001017911,0.0000344147],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988698,0.003285691,0.0002050021,0.0002778923,0.00005818966,0.00006277411,0.0002002309,0.00002791877,0.007184326],"genre_scores_gemma":[0.9985876,0.0004889212,0.0001983433,0.00008284346,0.00008300075,0.00001080221,0.0001228048,0.000002743441,0.0004229447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007065766,"threshold_uncertainty_score":0.01535672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02958031192698297,"score_gpt":0.3290382742697823,"score_spread":0.2994579623427993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}