{"id":"W1444073282","doi":"10.1016/j.expneurol.2015.07.018","title":"Intrinsic facilitation of adult peripheral nerve regeneration by the Sonic hedgehog morphogen","year":2015,"lang":"en","type":"article","venue":"Experimental Neurology","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hotchkiss Brain Institute; University of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Canadian HIV Trials Network, Canadian Institutes of Health Research; University of Calgary","keywords":"Sonic hedgehog; Axotomy; Morphogen; Neuroscience; Biology; Axon; Regeneration (biology); Peripheral nervous system; Sensory system; Gene knockdown; Sensory neuron; Growth cone; Cell biology; Anatomy; Central nervous system; Signal transduction; Cell culture","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001141004,0.0001439648,0.0001418647,0.00002052387,0.00007494957,0.000009246256,0.0001663682,0.0001099115,0.00001107653],"category_scores_gemma":[0.0001070569,0.0001160778,0.00006460397,0.00006203958,0.0002226147,0.000005052896,0.0001161869,0.00008189987,0.00001080873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001598923,"about_ca_system_score_gemma":0.00004819638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000618946,"about_ca_topic_score_gemma":0.00001892756,"domain_scores_codex":[0.9989588,0.000199159,0.0002267854,0.0002935172,0.0001321883,0.0001895947],"domain_scores_gemma":[0.9994498,0.000013552,0.0000904804,0.0002616852,0.0001275992,0.00005681373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002121183,0.00007188393,0.0006254035,0.000002853745,0.0000305037,0.000002356688,0.0007762877,0.0002022568,0.9873081,0.0001232347,0.0103053,0.0003397098],"study_design_scores_gemma":[0.0007159679,0.001501403,0.0001840827,0.000001217351,0.000004823735,0.00002811189,0.0005662797,0.0001505299,0.9895977,0.00003167514,0.00710644,0.0001117292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948442,0.003342489,0.000276426,0.0006589885,0.0003284794,0.000194814,0.00002472052,0.00001331503,0.0003165668],"genre_scores_gemma":[0.9984329,0.00002235145,0.00009516759,0.0008274456,0.0001695521,0.00005770281,0.000132102,0.00001728834,0.0002454757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003588714,"threshold_uncertainty_score":0.4733515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01967992080797705,"score_gpt":0.2644156143627449,"score_spread":0.2447356935547678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}