{"id":"W1455315711","doi":"10.3233/jad-2008-14309","title":"Adhesion of Exogenous Human Microglia and THP-1 Cells to Amyloid Plaques of Postmortem Alzheimer's Disease Brain","year":2008,"lang":"en","type":"article","venue":"Journal of Alzheimer s Disease","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Fondation pour la Recherche sur Alzheimer","keywords":"Microglia; THP1 cell line; Phagocytosis; Human brain; Lipopolysaccharide; Amyloid (mycology); Cell biology; Pathology; Alzheimer's disease; Chemistry; Cell culture; Neuroglia; Neuroinflammation; Biology; Immunology; Inflammation; Medicine; Central nervous system; Neuroscience; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003535203,0.0003054098,0.0002319147,0.0001892841,0.0003422137,0.0003325165,0.0001556366,0.0003081532,0.001420225],"category_scores_gemma":[0.0003647891,0.0001770731,0.0002119052,0.0001688874,0.0001947903,0.0001610868,0.0002971715,0.0003563577,0.0006525024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000209389,"about_ca_system_score_gemma":0.0001979034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001079808,"about_ca_topic_score_gemma":0.001545468,"domain_scores_codex":[0.9995822,0.000125169,0.00003312014,0.00006082334,0.00009487275,0.0001037862],"domain_scores_gemma":[0.9998803,0.00003577942,0.00001329959,0.00002998788,0.00002530162,0.00001524088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004667067,0.0001064329,0.001200869,0.0001458039,0.00001779468,0.0005438283,0.0001671161,0.0001020521,0.9937978,0.0001973289,0.0002221936,0.003032],"study_design_scores_gemma":[0.0001928863,0.003275654,0.05546299,0.0001774532,0.0001753366,0.005709751,0.001087288,0.0042057,0.9072357,0.0007738185,0.02165762,0.00004584511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836317,0.006990135,0.003520134,0.000190895,0.0001919537,0.00009832189,0.0005217779,0.000020642,0.004834374],"genre_scores_gemma":[0.9780617,0.004832371,0.01161423,0.0002150411,0.0001602483,0.0001889839,0.001353819,0.00001783555,0.003555914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001420225,"threshold_uncertainty_score":0.004751146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03952373306955098,"score_gpt":0.3155859284588166,"score_spread":0.2760621953892656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}