{"id":"W145853903","doi":"10.1016/j.radonc.2011.11.014","title":"Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells","year":2012,"lang":"en","type":"article","venue":"Radiotherapy and Oncology","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; McMaster University; Juravinski Cancer Centre","funders":"Canadian Institutes of Health Research; Hamilton Health Sciences Foundation","keywords":"AMPK; Protein kinase A; P70-S6 Kinase 1; Phosphorylation; Chemistry; PI3K/AKT/mTOR pathway; Cancer research; Protein kinase B; Kinase; Cell biology; Cancer cell; Molecular biology; Biology; Signal transduction; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001344569,0.0002376611,0.0002834317,0.0003966828,0.00022688,0.0005045095,0.0001659941,0.0003058334,0.001953742],"category_scores_gemma":[0.0001315007,0.0002242799,0.0004181241,0.0004107422,0.0001886179,0.0002629321,0.0001632954,0.0005230331,0.0005005691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003032271,"about_ca_system_score_gemma":0.0001679004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004867024,"about_ca_topic_score_gemma":0.0004075432,"domain_scores_codex":[0.9998497,0.00004084945,0.00001360186,0.00002785334,0.00003110968,0.00003686022],"domain_scores_gemma":[0.9999274,0.00001533061,0.00002067374,0.00001256884,0.00001038263,0.00001374025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009155571,0.00007368928,0.0008241778,0.00006687689,0.00002124132,0.00007954516,0.00003643684,0.000125221,0.9951828,0.0002775515,0.0001373741,0.002259634],"study_design_scores_gemma":[0.00008489544,0.0005949732,0.03590701,0.00002013048,0.00008595803,0.0004532451,0.0002005297,0.001365916,0.9552366,0.0002728346,0.005760599,0.00001720946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895997,0.006733953,0.001038499,0.0002690285,0.00008615436,0.00001411249,0.0003704625,0.00006088286,0.001827314],"genre_scores_gemma":[0.9926259,0.003376513,0.0005562468,0.0001285471,0.00002408387,0.00001919168,0.0005290387,0.00001622724,0.002724245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001953742,"threshold_uncertainty_score":0.006535947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01309959110117629,"score_gpt":0.2842178716848465,"score_spread":0.2711182805836702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}