{"id":"W1460422212","doi":"10.1164/rccm.201102-0192oc","title":"Effect of Five Genetic Variants Associated with Lung Function on the Risk of Chronic Obstructive Lung Disease, and Their Joint Effects on Lung Function","year":2011,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Ontario Institute for Cancer Research","funders":"NIHR Cambridge Biomedical Research Centre; Medical Research Council; University of Oxford; Asthma and Lung UK; Vetenskapsrådet; British Lung Foundation; Bundesministerium für Bildung und Forschung; National Institute for Health and Care Research; National Health and Medical Research Council; International Osteoporosis Foundation; Cancer Research UK; Healthway; Scottish Government; British Heart Foundation; Münchner Zentrum für Gesundheitswissenschaften; Tays; Wellcome Trust; University of Nottingham; Imperial College London; AstraZeneca","keywords":"Lung function; Medicine; Lung; Obstructive lung disease; COPD; Lung disease; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001082574,0.0005965212,0.0004040691,0.0009664532,0.00041822,0.0005191098,0.0003888864,0.0007244422,0.001927516],"category_scores_gemma":[0.002894357,0.0002178427,0.000780511,0.001003354,0.0006350442,0.0001453224,0.000486956,0.0004893223,0.0001260487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002426334,"about_ca_system_score_gemma":0.0002353143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003333864,"about_ca_topic_score_gemma":0.003690875,"domain_scores_codex":[0.9988508,0.0004512018,0.0001184772,0.0003562585,0.0001425878,0.000080716],"domain_scores_gemma":[0.9970827,0.001627924,0.0006230517,0.0002603486,0.0001080351,0.0002979121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001727838,0.00006091056,0.9878582,0.00003188284,0.0008646048,0.0001967091,0.00006922559,0.0002646364,0.006441914,0.00004409206,0.00003781222,0.002402209],"study_design_scores_gemma":[0.00009319802,0.0004154446,0.99685,0.000008936994,0.0004917919,0.0003769254,0.00004560238,0.0005436564,0.0009960505,0.00007564289,0.00009684474,0.000005851674],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993093,0.0002066519,0.0001889517,0.00002026564,0.00000250387,0.000004657936,0.0001325149,0.000003827683,0.0001313372],"genre_scores_gemma":[0.9994784,0.00003584562,0.0002494742,0.00001047834,0.000004918253,0.000006446827,0.0001477949,0.000001739832,0.00006490889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003333864,"threshold_uncertainty_score":0.006628931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01031392198183394,"score_gpt":0.2656999230342968,"score_spread":0.2553860010524629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}