{"id":"W1460819011","doi":"10.4049/jimmunol.194.supp.206.37","title":"Deep profiling of single T cell receptor repertoire and phenotype with targeted RNA-seq (TECH2P.927)","year":2015,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"T-cell receptor; Biology; CD8; T cell; Gene; Deep sequencing; FOXP3; Amplicon; Molecular biology; Genetics; Computational biology; Polymerase chain reaction; Antigen; Genome; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008836043,0.0006443184,0.0008506974,0.0004770622,0.0005443261,0.0009419515,0.0005919326,0.0006244664,0.004043773],"category_scores_gemma":[0.0005067895,0.0004136756,0.0007775764,0.0004921727,0.0003957282,0.0002665071,0.0006331176,0.001173248,0.002114062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003022954,"about_ca_system_score_gemma":0.000439334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009009427,"about_ca_topic_score_gemma":0.003164303,"domain_scores_codex":[0.9994492,0.00004722607,0.00002496281,0.0002530559,0.0001551524,0.00007037771],"domain_scores_gemma":[0.999714,0.0001034367,0.00003379923,0.00004954887,0.00006453615,0.00003455258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002473068,0.00004998731,0.003482486,0.0004054558,0.0001283108,0.0001145741,0.0001657405,0.00263881,0.9669403,0.0008235656,0.003752552,0.02125095],"study_design_scores_gemma":[0.0001373089,0.0005257693,0.0607798,0.00009612394,0.0003539625,0.0007225954,0.0002503188,0.1212312,0.7530529,0.00384726,0.05883161,0.0001710587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.4565376,0.001859028,0.4343059,0.0003431662,0.0003299657,0.0006696318,0.08058906,0.01524108,0.01012451],"genre_scores_gemma":[0.5024225,0.001017845,0.4111211,0.001345249,0.0001395156,0.002756739,0.06408031,0.005777141,0.01133961],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.004043773,"threshold_uncertainty_score":0.01352781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02779464675818661,"score_gpt":0.2699135668608347,"score_spread":0.2421189201026481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}