{"id":"W1479969203","doi":"10.18632/aging.100300","title":"The Werner syndrome helicase protein is required for cell proliferation, immortalization, and tumorigenesis in Scaffold Attachment Factor B1 deficient mice","year":2011,"lang":"en","type":"article","venue":"Aging","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research; U.S. Public Health Service","keywords":"Helicase; Carcinogenesis; Molecular biology; Biology; Cell cycle; RecQ helicase; Mutant; Telomere; Cell biology; Cell; Gene; Genetics; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000200124,0.0001210219,0.00008714787,0.00003235006,0.0001397303,0.00003610706,0.0001112396,0.00005527194,0.000006618459],"category_scores_gemma":[0.00002642791,0.00009714221,0.00003793486,0.00006897676,0.00002705208,0.000007177508,0.00006783304,0.00002352372,0.000002847139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002000292,"about_ca_system_score_gemma":0.00004144269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004138973,"about_ca_topic_score_gemma":0.00005037191,"domain_scores_codex":[0.9991202,0.00003536158,0.0002103954,0.0003183816,0.00009603356,0.0002196296],"domain_scores_gemma":[0.9995505,0.000006733795,0.00008053648,0.0002423137,0.00007164191,0.00004825461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006601263,0.0001091948,0.01244932,0.0000715969,0.00002528862,0.000008803268,0.0008610123,0.000004767069,0.9854141,0.0003015118,0.0001737233,0.0005146851],"study_design_scores_gemma":[0.0003664436,0.0001581188,0.002455217,0.00002102714,0.00001125079,0.00001676425,0.0001597402,0.0003209812,0.9948328,0.0001358751,0.00137322,0.0001485719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945244,0.0005302989,0.003791804,0.0001044979,0.00006572388,0.0008760925,0.00001384319,0.00001359687,0.00007980061],"genre_scores_gemma":[0.9972785,0.00003281451,0.001359799,0.0001570359,0.00002688795,0.0003103861,0.00002503054,0.00002253157,0.0007870585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009994108,"threshold_uncertainty_score":0.3961344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01805900281681601,"score_gpt":0.2460651738141056,"score_spread":0.2280061709972896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}