{"id":"W1480175705","doi":"10.4161/cbt.29187","title":"Dual VEGF/VEGFR inhibition in advanced solid malignancies","year":2014,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Cancer Institute","keywords":"Sunitinib; Medicine; Bevacizumab; Renal cell carcinoma; Thrombotic microangiopathy; Melanoma; Vascular endothelial growth factor; Internal medicine; Cancer; Oncology; Response Evaluation Criteria in Solid Tumors; Kidney cancer; Axitinib; Cancer research; Gastroenterology; Phases of clinical research; Chemotherapy; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001321036,0.0001741598,0.000346438,0.0001025437,0.00003695179,0.000004599077,0.0000342005,0.0001360866,0.0001772032],"category_scores_gemma":[0.0000145306,0.0001306878,0.00007459351,0.0001333042,0.0001292357,0.00003901898,0.00001524783,0.0001316681,0.00003809623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001898797,"about_ca_system_score_gemma":0.00008189886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009610977,"about_ca_topic_score_gemma":0.00007068048,"domain_scores_codex":[0.9989973,0.00008857883,0.0002180368,0.0003188014,0.00007242728,0.0003048273],"domain_scores_gemma":[0.9995092,0.00004510984,0.00007231618,0.000239405,0.00006114479,0.00007283896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008485233,0.0001538943,0.07474737,0.00002176705,0.00006623477,0.00004739181,0.000489444,0.00002793265,0.8482788,0.0004562823,0.000239497,0.07462285],"study_design_scores_gemma":[0.009150375,0.002878207,0.3262668,0.0002119617,0.00003285323,0.0000811283,0.0001122273,0.00004949577,0.6230075,0.001822409,0.03607343,0.0003136871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906455,0.006002792,0.00005925999,0.001473824,0.0002779204,0.0003593278,0.00000827497,0.00005119104,0.00112186],"genre_scores_gemma":[0.9942817,0.002567147,0.0001964763,0.00206408,0.0002847975,0.0002328548,0.00005681729,0.00002181528,0.0002943073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2515194,"threshold_uncertainty_score":0.5329295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02708406765607009,"score_gpt":0.3146572954899642,"score_spread":0.2875732278338941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}