{"id":"W1480175705","doi":"10.4161/cbt.29187","title":"Dual VEGF/VEGFR inhibition in advanced solid malignancies","year":2014,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Cancer Institute","keywords":"Sunitinib; Medicine; Bevacizumab; Renal cell carcinoma; Thrombotic microangiopathy; Melanoma; Vascular endothelial growth factor; Internal medicine; Cancer; Oncology; Response Evaluation Criteria in Solid Tumors; Kidney cancer; Axitinib; Cancer research; Gastroenterology; Phases of clinical research; Chemotherapy; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002996706,0.0002390934,0.0004741121,0.0001700839,0.0001105451,0.0002914198,0.0001452357,0.0001850462,0.0004892416],"category_scores_gemma":[0.0001309938,0.0000920368,0.0002289326,0.0001328562,0.0001461503,0.0001567196,0.0001700413,0.0006521182,0.0001588445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003562242,"about_ca_system_score_gemma":0.0002247721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002539604,"about_ca_topic_score_gemma":0.0007654498,"domain_scores_codex":[0.9998657,0.00003595052,0.00001010377,0.00002625921,0.00003218155,0.00002984379],"domain_scores_gemma":[0.9999214,0.00001161068,0.00002522508,0.000005545683,0.000008327652,0.0000278008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01111312,0.001775947,0.007321481,0.0007241205,0.0001813233,0.0007761547,0.0000776204,0.001785673,0.6938831,0.0004667544,0.001517531,0.2803771],"study_design_scores_gemma":[0.0156916,0.1216151,0.08383462,0.0001582548,0.0008931882,0.01886842,0.0001819823,0.01806769,0.6910577,0.00115872,0.04838614,0.00008665539],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840466,0.01331762,0.001143466,0.0001933823,0.00005732359,0.00006082421,0.00008147505,0.00005560525,0.001043699],"genre_scores_gemma":[0.9963786,0.002004925,0.0008580464,0.00007477354,0.00002972406,0.00003070963,0.0001269789,0.000005182581,0.0004911393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004892416,"threshold_uncertainty_score":0.002584636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02708406765607009,"score_gpt":0.3146572954899642,"score_spread":0.2875732278338941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}