{"id":"W1480257879","doi":"10.1002/bip.22498","title":"Stability and degradation patterns of chemically modified analogs of apelin‐13 in plasma and cerebrospinal fluid","year":2014,"lang":"en","type":"article","venue":"Biopolymers","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Apelin; Chemistry; Proteases; Cleavage (geology); Protease; Bond cleavage; Hydrolysis; Receptor; Peptide; Biochemistry; Peptide bond; Amino acid; In vivo; Ligand (biochemistry); Enzyme; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002025037,0.0002083252,0.0001410395,0.0001390715,0.00007993959,0.0001507806,0.0001104069,0.0002216741,0.0006632876],"category_scores_gemma":[0.0004082924,0.00006995377,0.0002012995,0.0001238126,0.0001445635,0.000172668,0.00006974828,0.0003217609,0.0001450436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001411504,"about_ca_system_score_gemma":0.00008932003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002613383,"about_ca_topic_score_gemma":0.0001622838,"domain_scores_codex":[0.9998903,0.00002333115,0.00001235917,0.00002679927,0.0000281231,0.00001904707],"domain_scores_gemma":[0.999765,0.00004764817,0.0001042432,0.00001951706,0.00003175245,0.00003182879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006883845,0.00002573342,0.0002519031,0.00003561125,0.00001348357,0.00007753712,0.00002611805,0.0001315408,0.9971853,0.00003545151,0.0000165064,0.001512383],"study_design_scores_gemma":[0.00001724456,0.001087387,0.004023165,0.00000649145,0.00002588001,0.0003788174,0.00002762698,0.0008033296,0.9926513,0.00003300902,0.0009362918,0.000009521134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971206,0.001309717,0.001152086,0.00001876386,0.00001029117,0.000008310458,0.0001380507,0.000006747675,0.0002353967],"genre_scores_gemma":[0.9955687,0.001077331,0.001954903,0.00003213604,0.000008014443,0.00001966731,0.0004174104,0.000009185704,0.000912604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006632876,"threshold_uncertainty_score":0.002218902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02116729973135347,"score_gpt":0.2778265469509372,"score_spread":0.2566592472195838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}