{"id":"W1480257879","doi":"10.1002/bip.22498","title":"Stability and degradation patterns of chemically modified analogs of apelin‐13 in plasma and cerebrospinal fluid","year":2014,"lang":"en","type":"article","venue":"Biopolymers","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Apelin; Chemistry; Proteases; Cleavage (geology); Protease; Bond cleavage; Hydrolysis; Receptor; Peptide; Biochemistry; Peptide bond; Amino acid; In vivo; Ligand (biochemistry); Enzyme; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004233865,0.0001013939,0.0002975123,0.0001351659,0.00001416515,0.000003470234,0.00006407723,0.0001645981,0.00008241199],"category_scores_gemma":[0.0004769468,0.00008318709,0.00003293814,0.0001870348,0.0003897164,0.00003515802,0.00006216935,0.000172131,0.000001083794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003166839,"about_ca_system_score_gemma":0.00006962206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007766241,"about_ca_topic_score_gemma":0.00004838406,"domain_scores_codex":[0.9987741,0.0000535834,0.0003806202,0.0002431721,0.000352879,0.0001956584],"domain_scores_gemma":[0.9993147,0.0001611931,0.00008413882,0.0001835928,0.00007184269,0.0001844968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005549964,0.0001422279,0.2214147,0.000368047,0.00002744624,0.000001681812,0.0001362776,1.715352e-7,0.7507421,0.0001320709,0.00001255276,0.02646769],"study_design_scores_gemma":[0.003078869,0.0005836451,0.6045128,0.0002015393,0.00004100833,0.000007150703,0.0002415711,0.006725048,0.3844009,0.0000717161,0.00002881997,0.0001069123],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984829,0.0002019809,0.0003085001,0.0004945751,0.00002138454,0.0001951097,0.00001777359,0.000009039767,0.0002687216],"genre_scores_gemma":[0.9995108,0.0001430571,0.0002085813,0.00004070848,0.00001852186,0.000003639244,0.00003056763,0.000008786555,0.00003528693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3830981,"threshold_uncertainty_score":0.3392271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02116729973135347,"score_gpt":0.2778265469509372,"score_spread":0.2566592472195838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}