{"id":"W1481370239","doi":"10.1186/ar1582","title":"Oncostatin M in rheumatoid arthritis: a key cytokine acts synergistically with other proinflammatory cytokines to promote human cartilage loss","year":2005,"lang":"en","type":"article","venue":"Arthritis Research","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Center for Research Resources; National Institutes of Health; Deutsches Krebsforschungszentrum; Dutch Arthritis Association; Hungarian Scientific Research Fund; Vlaamse regering; Studienstiftung des Deutschen Volkes; Deutsche Forschungsgemeinschaft; Queen Mary University of London; Cancer Research UK; Wellcome Trust; Fondation pour la Recherche Médicale; Northwestern University","keywords":"Oncostatin M; Rheumatoid arthritis; Angiogenesis; Inflammation; Cytokine; Interleukin 6; Cartilage; Medicine; Immunology; Cancer research; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001642642,0.0003267406,0.0002680373,0.0002528503,0.0001213221,0.00025396,0.0001051201,0.0002307022,0.001180066],"category_scores_gemma":[0.0001177508,0.00008691786,0.0002564598,0.0001656273,0.0002382169,0.0001664428,0.0002738806,0.0003985372,0.0002716921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002261153,"about_ca_system_score_gemma":0.0001975439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002603222,"about_ca_topic_score_gemma":0.0004771238,"domain_scores_codex":[0.9998771,0.00002828403,0.00001145625,0.000009425597,0.00002786659,0.00004589704],"domain_scores_gemma":[0.9999022,0.00001662522,0.0000238478,0.000006519701,0.00000506338,0.0000457744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009197111,0.00006976687,0.001059059,0.0001270374,0.0000113797,0.0005092839,0.00001984856,0.00006581487,0.9879419,0.0001937902,0.0002071912,0.008875256],"study_design_scores_gemma":[0.0002169066,0.004772448,0.0226968,0.00002065049,0.0000814906,0.003756657,0.00008517805,0.0004118088,0.9592166,0.0001638239,0.008569227,0.000008309717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873727,0.009404519,0.0007654096,0.0002300292,0.00009160871,0.0000242831,0.0001577594,0.00005896045,0.001894755],"genre_scores_gemma":[0.9936634,0.004184466,0.000726235,0.00005581978,0.00006688263,0.00001852713,0.0001726179,0.000005168661,0.001106812],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001180066,"threshold_uncertainty_score":0.003947675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03723969400627544,"score_gpt":0.347599378526377,"score_spread":0.3103596845201016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}