{"id":"W1481377573","doi":"10.1007/978-1-60327-547-7_18","title":"Protein Components of the microRNA Pathway and Human Diseases","year":2008,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Drosha; Dicer; Argonaute; Biology; microRNA; RNA-binding protein; Translation (biology); Genetics; Biogenesis; Messenger RNA; RNA interference; Cell biology; RNA; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000168273,0.0003529868,0.0007908994,0.0000954557,0.00006512586,0.000005609497,0.0004651518,0.0003842651,0.000003072128],"category_scores_gemma":[0.0001124293,0.000255137,0.0003132141,0.0001609302,0.0003782345,5.988298e-7,0.0006149527,0.000205653,6.757855e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001203452,"about_ca_system_score_gemma":0.0001314714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001853099,"about_ca_topic_score_gemma":0.000006337568,"domain_scores_codex":[0.9972106,0.001386609,0.0005119184,0.0005656426,0.00006670133,0.0002585563],"domain_scores_gemma":[0.9990965,0.00002333012,0.000283273,0.0005172162,0.00002599169,0.00005373675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000506337,0.0000815603,0.0001524155,0.0008750805,0.00008431329,0.000005795531,0.000007348775,4.047533e-7,0.8287394,0.0001869151,0.00001862005,0.1698431],"study_design_scores_gemma":[0.0003345606,0.0001633904,0.0006595321,0.000745466,0.00006488357,0.00005121628,0.000003715002,3.490428e-7,0.04580928,0.0003579639,0.9513967,0.0004129469],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006896474,0.9897109,0.002247084,0.00001008734,0.0001086683,0.0008265665,0.00007038793,0.000003699941,0.0001261249],"genre_scores_gemma":[0.0004117337,0.965705,0.03331762,0.00006693821,0.00001127086,0.0001230337,0.0002246695,0.00005112528,0.0000885671],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.951378,"threshold_uncertainty_score":0.9999901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03628498192312824,"score_gpt":0.369842082109055,"score_spread":0.3335571001859268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}