{"id":"W1482253718","doi":"10.1158/1538-7445.am2015-117","title":"Abstract 117: DOT1L is a human chromosome stability gene","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Biology; Mitosis; Histone; Cell biology; Histone H2B; Epigenetics; Genetics; Histone methyltransferase; Ubiquitin; Ubiquitin ligase; Histone H3; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004838208,0.0003039855,0.0001817781,0.0002829412,0.0003806975,0.0002423051,0.0002012855,0.0004453053,0.00712837],"category_scores_gemma":[0.0001339471,0.0001227833,0.000168945,0.0002348436,0.0001807104,0.00009437555,0.0002849947,0.0003450383,0.00287627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005826515,"about_ca_system_score_gemma":0.0001943914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001250483,"about_ca_topic_score_gemma":0.001400506,"domain_scores_codex":[0.9999098,0.000005796419,0.000006397696,0.00003901158,0.000029712,0.000009314588],"domain_scores_gemma":[0.9999357,0.0000126137,0.00001935176,0.000005648593,0.000008183023,0.0000184735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001261576,0.00002939151,0.002464122,0.00009740463,0.00001188057,0.001530104,0.0000387375,0.000167209,0.9847128,0.0004354545,0.001357672,0.009029013],"study_design_scores_gemma":[0.00006975204,0.000275265,0.06325336,0.00003466785,0.00005096593,0.009919344,0.0001091888,0.003882497,0.8290437,0.0003904361,0.09294883,0.00002188395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9551836,0.003610273,0.01154375,0.0009964503,0.0003069004,0.0001381905,0.01059799,0.0007207459,0.01690215],"genre_scores_gemma":[0.9552307,0.0006880972,0.003901944,0.0003121756,0.00002963128,0.0001075022,0.01100801,0.000108363,0.02861367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00712837,"threshold_uncertainty_score":0.02384675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1969304908049955,"score_gpt":0.4524099855965256,"score_spread":0.2554794947915301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}