{"id":"W1482347462","doi":"10.4049/jimmunol.0902725","title":"Predominant Expression of CCL2 at the Tumor Site of Prostate Cancer Patients Directs a Selective Loss of Immunological Tolerance to CCL2 That Could Be Amplified in a Beneficial Manner","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Israel Science Foundation","keywords":"Prostate cancer; Chemokine; Cancer; Immune system; CCL2; Malignancy; Immunology; CCL5; Medicine; Disease; Prostate; Cancer research; Biology; IL-2 receptor; Pathology; Internal medicine; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000997061,0.0003100356,0.00104331,0.0002843878,0.0001811608,0.000005040098,0.0007494788,0.0002785102,0.0001603849],"category_scores_gemma":[0.0002857056,0.0001692273,0.0002413108,0.0004021325,0.0007927,0.0001243662,0.0002085303,0.0007234892,0.000006878761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001390114,"about_ca_system_score_gemma":0.0001775791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003201609,"about_ca_topic_score_gemma":0.00006143058,"domain_scores_codex":[0.9965737,0.001313126,0.001247454,0.000207968,0.0001486459,0.0005091417],"domain_scores_gemma":[0.9965821,0.0007391467,0.001697741,0.0004611146,0.0005043554,0.00001555182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.05244839,0.0008556556,0.006063471,0.00001890251,0.0002931958,0.000005879082,0.008826645,0.0002260279,0.9270932,0.00004379809,0.0002070373,0.003917808],"study_design_scores_gemma":[0.003925306,0.003502937,0.2319711,0.0003863267,0.00006798455,0.0001240676,0.0005833856,0.000001091254,0.7581207,0.00008961833,0.001083853,0.0001436509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9669786,0.0309303,0.00001206894,0.0008275969,0.0004765568,0.0006435603,0.00008348659,0.000007021818,0.00004080248],"genre_scores_gemma":[0.9961396,0.003220835,0.00002675284,0.0002190607,0.00001446769,0.00001957483,0.000008024894,0.0000185376,0.0003330781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2259076,"threshold_uncertainty_score":0.6900888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078639890518471,"score_gpt":0.2529288255317303,"score_spread":0.2421424266265456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}