{"id":"W1482617484","doi":"10.4049/jimmunol.166.5.3174","title":"Ligation of 4-1BB (CDw137) Regulates Graft-Versus-Host Disease, Graft-Versus-Leukemia, and Graft Rejection in Allogeneic Bone Marrow Transplant Recipients","year":2001,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":144,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research & Development Corporation","funders":"National Institute of Dental and Craniofacial Research; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; Memorial Sloan-Kettering Cancer Center","keywords":"CD8; T cell; Leukemia; Immunology; Bone marrow; Cytotoxic T cell; CD28; Graft-versus-host disease; Splenocyte; Transplantation; Cancer research; Medicine; Biology; Immune system; Internal medicine; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001652807,0.0003451512,0.0002896807,0.0002235263,0.0001474475,0.0002995821,0.0001857087,0.0002484818,0.001134479],"category_scores_gemma":[0.0002332946,0.0001538236,0.0001884994,0.00009310668,0.0002090594,0.0001842875,0.0001554297,0.0006739669,0.0002824835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002724578,"about_ca_system_score_gemma":0.0002410123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003469568,"about_ca_topic_score_gemma":0.0003758137,"domain_scores_codex":[0.9998009,0.00004620068,0.00001706348,0.00002148613,0.00003925804,0.00007519684],"domain_scores_gemma":[0.9998715,0.00001580688,0.00003460673,0.000006348526,0.000008462761,0.00006332324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008542552,0.0002824523,0.001129114,0.00003347497,0.00001007889,0.00008406343,0.00002454904,0.0001521941,0.9948871,0.0001519315,0.00005313547,0.002337691],"study_design_scores_gemma":[0.0003836195,0.00754937,0.04905949,0.00002389528,0.0001654061,0.001059539,0.0001368075,0.005516043,0.9334661,0.000371382,0.002249773,0.0000186688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989262,0.0004278359,0.0002433557,0.00002899808,0.000008331027,0.000006927317,0.00002514529,0.00002108454,0.0003120264],"genre_scores_gemma":[0.9985782,0.0002445619,0.0001833226,0.00002891864,0.000009401178,0.00001961256,0.00007910242,0.000005020895,0.0008518087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001134479,"threshold_uncertainty_score":0.003795207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01228470242953559,"score_gpt":0.2211014019295588,"score_spread":0.2088166995000233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}