{"id":"W1483142573","doi":"10.1002/9780470889909.ch23","title":"Epigenetic Analysis of Pluripotent Cells","year":2010,"lang":"en","type":"other","venue":"","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Reprogramming; Epigenetics; Chromatin; DNA methylation; Biology; Epigenetic regulation of neurogenesis; Epigenomics; Histone; Induced pluripotent stem cell; Genetics; Cell biology; Computational biology; Chromatin remodeling; DNA; Embryonic stem cell; Cell; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000371638,0.0002901725,0.0002671461,0.0005120397,0.0002357516,0.0005349684,0.0003467209,0.0002438545,0.008415297],"category_scores_gemma":[0.0001695143,0.0001336394,0.0002906617,0.000422931,0.0002087475,0.0003528819,0.0003965292,0.000739924,0.002256606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004029271,"about_ca_system_score_gemma":0.0002549848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004991916,"about_ca_topic_score_gemma":0.001013966,"domain_scores_codex":[0.9998029,0.00002659567,0.00001265796,0.0000381379,0.0001021698,0.00001762367],"domain_scores_gemma":[0.9999385,0.00001313442,0.000006601941,0.00001356249,0.00002047923,0.000007714477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007046877,0.00002110182,0.000423709,0.0002792564,0.0000197371,0.0001588647,0.00005270704,0.0002532016,0.9111167,0.008164618,0.002668008,0.07677151],"study_design_scores_gemma":[0.000009495464,0.00007108386,0.004943244,0.00003959969,0.00003845197,0.0004767271,0.00004363696,0.0005646624,0.80603,0.002237638,0.1855325,0.00001301173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2177276,0.09614034,0.3980035,0.004830098,0.002772458,0.0006345321,0.02402682,0.003005574,0.2528591],"genre_scores_gemma":[0.3982636,0.09359772,0.1508329,0.002570724,0.0005706203,0.000461261,0.02167294,0.0008894761,0.3311407],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.008415297,"threshold_uncertainty_score":0.02815205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00558221905085377,"score_gpt":0.2392090618567281,"score_spread":0.2336268428058743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}