{"id":"W1483233132","doi":"10.1002/9781118697191.ch15","title":"Ruthenium Anticancer Compounds with Biologically‐derived Ligands","year":2014,"lang":"en","type":"other","venue":"","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Ruthenium; Combinatorial chemistry; Ligand (biochemistry); Chemistry; Rational design; Biological activity; Anticancer drug; Drug discovery; In vitro; Stereochemistry; Nanotechnology; Biochemistry; Drug; Biology; Materials science; Pharmacology; Receptor; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003178804,0.0004904302,0.0004360675,0.0002844303,0.0001581105,0.0005480071,0.0006679794,0.0006541765,0.003124165],"category_scores_gemma":[0.0002697272,0.0002715269,0.000302868,0.0003607616,0.0003763194,0.0005271105,0.0006202955,0.0009938669,0.002751685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000691034,"about_ca_system_score_gemma":0.0002781566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002700512,"about_ca_topic_score_gemma":0.0003787132,"domain_scores_codex":[0.9997371,0.00008969039,0.00001825173,0.00004572426,0.00006299491,0.00004627206],"domain_scores_gemma":[0.9998803,0.00002315611,0.00004242651,0.00001932885,0.00001547115,0.00001929139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000235925,0.0001781649,0.0001306589,0.001151003,0.00003181557,0.0002877387,0.00009558586,0.002127963,0.917347,0.02062464,0.003196022,0.05459349],"study_design_scores_gemma":[0.0001232515,0.0007148175,0.0002255081,0.00008313173,0.00003384811,0.0004613405,0.00002331653,0.001335757,0.7983814,0.001260396,0.1973215,0.00003567682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4957994,0.1943927,0.1518261,0.00629628,0.001418296,0.0009469287,0.001600603,0.003086501,0.1446332],"genre_scores_gemma":[0.8268544,0.06733988,0.06921668,0.002464826,0.000350141,0.0007934126,0.001216182,0.0002674785,0.03149705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003124165,"threshold_uncertainty_score":0.01045144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02999416103909497,"score_gpt":0.2484528231868057,"score_spread":0.2184586621477107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}