{"id":"W1483233132","doi":"10.1002/9781118697191.ch15","title":"Ruthenium Anticancer Compounds with Biologically‐derived Ligands","year":2014,"lang":"en","type":"other","venue":"","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Ruthenium; Combinatorial chemistry; Ligand (biochemistry); Chemistry; Rational design; Biological activity; Anticancer drug; Drug discovery; In vitro; Stereochemistry; Nanotechnology; Biochemistry; Drug; Biology; Materials science; Pharmacology; Receptor; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001156324,0.000317065,0.000818172,0.0001121122,0.00003405713,0.00002559782,0.000135152,0.0002385676,0.01764543],"category_scores_gemma":[0.00002613085,0.0001489057,0.0001090274,0.00007315859,0.0002283091,0.000008426083,0.00004536422,0.0001771643,0.0005707134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001316179,"about_ca_system_score_gemma":0.00004783573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001238659,"about_ca_topic_score_gemma":0.00005411068,"domain_scores_codex":[0.9989379,0.00003526958,0.0001948988,0.0003577284,0.0002267771,0.0002474142],"domain_scores_gemma":[0.999209,0.00004545909,0.0001173773,0.0004679718,0.00004232105,0.0001178113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006511093,0.0001826034,0.001841353,0.0005686547,0.0007830028,0.00002034818,0.00004320194,1.263572e-7,0.1004486,0.001847476,0.8910826,0.002530963],"study_design_scores_gemma":[0.0006023782,0.0007443927,0.0006969427,0.0005597079,0.0001812348,0.0000369925,0.00001753616,0.00001694544,0.009029528,0.00002866341,0.9877665,0.000319176],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.001904955,0.00121306,0.0005148668,0.0005208715,0.0001288858,0.0003258027,0.00000860881,0.0003132975,0.9950696],"genre_scores_gemma":[0.1495646,0.0003023813,0.003457146,0.001446831,0.0005666142,0.00002324637,0.00004069493,0.000286285,0.8443122],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.1507574,"threshold_uncertainty_score":0.9832526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02999416103909497,"score_gpt":0.2484528231868057,"score_spread":0.2184586621477107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}