{"id":"W1483418607","doi":"10.1038/cddis.2015.145","title":"Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virus","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Lady Davis Institute for Medical Research; Associazione Italiana per la Ricerca sul Cancro; Jewish General Hospital; Institut Català de Nanociència i Nanotecnologia","keywords":"Lytic cycle; Biology; BZLF1; Telomerase reverse transcriptase; Telomerase; Notch signaling pathway; Gene silencing; Cell biology; Epstein–Barr virus; Telomere; Transcription factor; Cancer research; Signal transduction; Virology; Virus; Genetics; Herpesviridae; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002643734,0.0001266278,0.0002576405,0.00004339195,0.00006232363,0.00001615515,0.0001391552,0.00004562036,0.000007613049],"category_scores_gemma":[0.0001214015,0.00006194694,0.00005142254,0.0001514098,0.0003545909,0.00005312111,0.00008500845,0.0001101763,6.290231e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007152293,"about_ca_system_score_gemma":0.0001182378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006104426,"about_ca_topic_score_gemma":0.00002508961,"domain_scores_codex":[0.999069,0.00006588018,0.0002635579,0.0001779536,0.0002543824,0.000169214],"domain_scores_gemma":[0.9990779,0.0001366507,0.0001063525,0.0003606246,0.0000622174,0.0002562859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002701729,0.0001443919,0.9875317,0.0002394825,0.00001690844,0.00001256874,0.001482237,0.000003031514,0.004987296,0.00004641107,0.00003270145,0.005233159],"study_design_scores_gemma":[0.001482422,0.00009503662,0.9861677,0.00008923365,0.0001773193,0.000006784259,0.0006633562,0.0001955131,0.009616671,0.0009766141,0.0004508286,0.00007846927],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916015,0.007256258,0.000002760856,0.0003299413,0.0000230869,0.0003366876,0.00007640819,0.000004886134,0.0003685036],"genre_scores_gemma":[0.9993429,0.0002842301,0.00001663576,0.0002003072,0.00003838326,0.000006912753,0.000006482279,0.000009232026,0.00009490427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007741445,"threshold_uncertainty_score":0.2526123,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01706961299553541,"score_gpt":0.2594549556172794,"score_spread":0.242385342621744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}