{"id":"W1483418607","doi":"10.1038/cddis.2015.145","title":"Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virus","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Lady Davis Institute for Medical Research; Associazione Italiana per la Ricerca sul Cancro; Jewish General Hospital; Institut Català de Nanociència i Nanotecnologia","keywords":"Lytic cycle; Biology; BZLF1; Telomerase reverse transcriptase; Telomerase; Notch signaling pathway; Gene silencing; Cell biology; Epstein–Barr virus; Telomere; Transcription factor; Cancer research; Signal transduction; Virology; Virus; Genetics; Herpesviridae; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002247356,0.0002314383,0.0002094493,0.0002173094,0.0001605653,0.0006607748,0.0001746209,0.0002978525,0.000610622],"category_scores_gemma":[0.0001128008,0.0001355911,0.0002058831,0.000177266,0.0001759162,0.0005826589,0.0003356746,0.0004105612,0.0001558832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002976271,"about_ca_system_score_gemma":0.0001537259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002151452,"about_ca_topic_score_gemma":0.0002855996,"domain_scores_codex":[0.999841,0.00003157838,0.00001580503,0.00003938878,0.00004027977,0.00003193358],"domain_scores_gemma":[0.9999408,0.00001057997,0.00001695287,0.000006138395,0.000008734801,0.00001689055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000214582,0.00001798941,0.000739679,0.00005805242,0.000008056972,0.0001121333,0.00002625028,0.00006472338,0.9947464,0.0003380156,0.00002677019,0.003647236],"study_design_scores_gemma":[0.00003266344,0.0002832083,0.02232256,0.00002720375,0.00005020346,0.001122586,0.0001593431,0.002837659,0.967521,0.000617179,0.005010321,0.00001624187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9772426,0.01759756,0.003105836,0.0001401836,0.00002819154,0.00001631831,0.0001623921,0.000031091,0.001675795],"genre_scores_gemma":[0.9934945,0.00333471,0.001129857,0.00006250819,0.00001974408,0.00001590076,0.0001889486,0.00000742077,0.001746537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006607748,"threshold_uncertainty_score":0.002159417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01706961299553541,"score_gpt":0.2594549556172794,"score_spread":0.242385342621744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}