{"id":"W1483922385","doi":"10.1002/stem.1979","title":"Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway","year":2015,"lang":"en","type":"article","venue":"Stem Cells","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Manitoba Medical Service Foundation; Manitoba Health Research Council; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Downregulation and upregulation; Cell biology; Biology; Chondroitin sulfate proteoglycan; Neural stem cell; Extracellular matrix; Neuroscience; Stem cell; Proteoglycan; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000828886,0.0003826439,0.0001817762,0.0001711828,0.0001235551,0.0002008572,0.0001353448,0.000147831,0.0007330609],"category_scores_gemma":[0.000071803,0.00007644616,0.0002302416,0.00009105125,0.0002128839,0.0001273875,0.0001458876,0.0003858564,0.0001718083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002061514,"about_ca_system_score_gemma":0.0002695007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001055511,"about_ca_topic_score_gemma":0.001854877,"domain_scores_codex":[0.9998552,0.00002826575,0.00001455393,0.0000167221,0.00004158946,0.00004371568],"domain_scores_gemma":[0.9999355,0.000004405005,0.00002294033,0.000005028804,0.000009241078,0.000022879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001266259,0.00003070381,0.0001954616,0.00006885771,0.000006630926,0.00005094886,0.00001282811,0.00003528972,0.9981413,0.00005911445,0.00003396095,0.001238272],"study_design_scores_gemma":[0.00002035896,0.0004127934,0.01302531,0.00001004037,0.00002783706,0.0001181632,0.00004549893,0.0004795982,0.9843812,0.00003781326,0.001437421,0.00000408071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994509,0.002249671,0.0008232012,0.00009548833,0.00002498525,0.00002593334,0.000158704,0.00004416137,0.002068874],"genre_scores_gemma":[0.9952794,0.001641615,0.0004511594,0.00005392035,0.00001063461,0.00004174923,0.0001883275,0.000006868579,0.002326301],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001055511,"threshold_uncertainty_score":0.002452314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0268475096145699,"score_gpt":0.26262191568173,"score_spread":0.2357744060671601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}