{"id":"W1484121608","doi":"10.1002/cncr.23813","title":"Temozolomide rechallenge in recurrent malignant glioma by using a continuous temozolomide schedule","year":2008,"lang":"en","type":"article","venue":"Cancer","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Temozolomide; Medicine; Concomitant; Anaplastic astrocytoma; Internal medicine; Glioma; Dacarbazine; Progression-free survival; Oncology; Adjuvant; Radiation therapy; Surgery; Chemotherapy; Astrocytoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004167183,0.0002145215,0.0002904304,0.0002224259,0.0001091174,0.000155751,0.0003467539,0.0001620531,0.0005598056],"category_scores_gemma":[0.0004763805,0.0000820725,0.0002645472,0.00017752,0.0002001707,0.000182248,0.0001674714,0.0003109074,0.0001395091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004597713,"about_ca_system_score_gemma":0.000261218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00154379,"about_ca_topic_score_gemma":0.002930731,"domain_scores_codex":[0.9998567,0.0000445421,0.00001127813,0.00002651914,0.00002553799,0.00003539291],"domain_scores_gemma":[0.9998676,0.00003737593,0.00003545579,0.00001853368,0.000009435931,0.00003174814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.01554129,0.002093667,0.05236934,0.001068959,0.0004112139,0.006388177,0.0006712157,0.005099055,0.3623374,0.0004661105,0.002006578,0.5515469],"study_design_scores_gemma":[0.00781807,0.2045998,0.4407629,0.0001623016,0.001660595,0.04305543,0.0003361789,0.01264594,0.2471149,0.0004926343,0.04126019,0.0000910295],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944563,0.003574675,0.001194636,0.00005131906,0.00001380207,0.00006066583,0.00003069941,0.00005304054,0.0005649381],"genre_scores_gemma":[0.9979604,0.0009340887,0.0007337877,0.00002082316,0.00002046823,0.00002635852,0.00009913997,0.000007353302,0.0001975995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00154379,"threshold_uncertainty_score":0.003335893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05534623594769785,"score_gpt":0.3178142414814136,"score_spread":0.2624680055337157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}