{"id":"W1484121608","doi":"10.1002/cncr.23813","title":"Temozolomide rechallenge in recurrent malignant glioma by using a continuous temozolomide schedule","year":2008,"lang":"en","type":"article","venue":"Cancer","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Temozolomide; Medicine; Concomitant; Anaplastic astrocytoma; Internal medicine; Glioma; Dacarbazine; Progression-free survival; Oncology; Adjuvant; Radiation therapy; Surgery; Chemotherapy; Astrocytoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000128246,0.000246639,0.0005277737,0.0001755571,0.00008958951,0.00001046435,0.00008437202,0.0001212288,0.0002174959],"category_scores_gemma":[0.00005752823,0.0002045857,0.0001203009,0.0003237365,0.00008955984,0.00007478149,0.00004300119,0.0001810623,0.00004434559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006080343,"about_ca_system_score_gemma":0.0001737265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005686853,"about_ca_topic_score_gemma":0.0001620992,"domain_scores_codex":[0.9984109,0.00005246921,0.0003806706,0.0004543349,0.0002456178,0.0004559443],"domain_scores_gemma":[0.999231,0.00005070108,0.0001186609,0.0003284022,0.00007393157,0.0001973198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009029378,0.003021018,0.4312487,0.0002022513,0.0003984371,0.007150974,0.001222753,0.00007375834,0.4924952,0.000135267,0.02870111,0.03444766],"study_design_scores_gemma":[0.03285358,0.001870735,0.1295279,0.004113761,0.0007177931,0.003581993,0.0009297795,0.002041714,0.7606147,0.0001320149,0.06175111,0.001864911],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9690754,0.02815349,0.00001080532,0.001270583,0.0003383704,0.0005955021,0.00004143251,0.00005645962,0.0004579247],"genre_scores_gemma":[0.9956114,0.002927447,0.0006170703,0.0002779964,0.0001412355,0.0002423092,0.0000203534,0.00004149299,0.0001206679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3017207,"threshold_uncertainty_score":0.8342762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05534623594769785,"score_gpt":0.3178142414814136,"score_spread":0.2624680055337157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}