{"id":"W1484489534","doi":"10.4049/jimmunol.168.3.1419","title":"Mechanisms Involved in Spontaneous and <i>Viscum album</i> Agglutinin-I-Induced Human Neutrophil Apoptosis: <i>Viscum album</i> Agglutinin-I Accelerates the Loss of Antiapoptotic Mcl-1 Expression and the Degradation of Cytoskeletal Paxillin and Vimentin Proteins Via Caspases","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Biology; Cell biology; Apoptosis; Brefeldin A; Caspase; Vinculin; Inhibitor of apoptosis domain; Intrinsic apoptosis; Agglutinin; Molecular biology; Programmed cell death; Signal transduction; Biochemistry; Lectin; Golgi apparatus; Endoplasmic reticulum; Focal adhesion","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001829081,0.0004203228,0.0009910666,0.0002450543,0.0005483343,0.0000373741,0.0006589994,0.0003793132,0.00008614046],"category_scores_gemma":[0.000183971,0.000221649,0.0001591019,0.00024322,0.001410803,0.0002413995,0.0004103119,0.001023515,0.000003836703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003036792,"about_ca_system_score_gemma":0.00004398355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003958452,"about_ca_topic_score_gemma":0.0001008527,"domain_scores_codex":[0.995935,0.00174827,0.00134506,0.0002994724,0.0001481629,0.000524074],"domain_scores_gemma":[0.9969465,0.0007368358,0.001571325,0.0005247435,0.0001867068,0.0000339201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001274916,0.0002572801,0.0001072328,0.00003884938,0.0003663228,0.00001562542,0.002234302,0.000007161549,0.9921611,0.001525702,0.00003438739,0.001977148],"study_design_scores_gemma":[0.006840988,0.002064031,0.002319583,0.0003172983,0.0003175216,0.002601436,0.00316175,0.00004489913,0.980203,0.001777309,0.00008933329,0.0002629046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797924,0.01736031,0.0002533361,0.001390141,0.0003468778,0.0007984073,0.00001509087,0.00001367826,0.00002975949],"genre_scores_gemma":[0.9947301,0.004722138,0.0001807288,0.0001529275,0.00002690971,0.00002140505,0.000007915621,0.00003680221,0.0001210826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01493769,"threshold_uncertainty_score":0.9038582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01390108094005238,"score_gpt":0.2157815853515885,"score_spread":0.2018805044115361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}