{"id":"W1484489534","doi":"10.4049/jimmunol.168.3.1419","title":"Mechanisms Involved in Spontaneous and <i>Viscum album</i> Agglutinin-I-Induced Human Neutrophil Apoptosis: <i>Viscum album</i> Agglutinin-I Accelerates the Loss of Antiapoptotic Mcl-1 Expression and the Degradation of Cytoskeletal Paxillin and Vimentin Proteins Via Caspases","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Biology; Cell biology; Apoptosis; Brefeldin A; Caspase; Vinculin; Inhibitor of apoptosis domain; Intrinsic apoptosis; Agglutinin; Molecular biology; Programmed cell death; Signal transduction; Biochemistry; Lectin; Golgi apparatus; Endoplasmic reticulum; Focal adhesion","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001660029,0.0004017676,0.000259548,0.000221348,0.0001710055,0.0003236993,0.000228598,0.0005277862,0.0008646889],"category_scores_gemma":[0.0001506138,0.0001314731,0.000488469,0.0001389169,0.0002885528,0.0004128072,0.0002186692,0.0005065618,0.0002757864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004432354,"about_ca_system_score_gemma":0.0001701798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000256556,"about_ca_topic_score_gemma":0.0002217398,"domain_scores_codex":[0.99984,0.00003995263,0.0000185061,0.00002621552,0.00002707946,0.00004822209],"domain_scores_gemma":[0.9998757,0.00001147007,0.00006399435,0.0000130848,0.00001624101,0.00001951494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003705642,0.00004870517,0.0006207636,0.000107092,0.00001572284,0.000211902,0.00003456258,0.00006483927,0.9966986,0.0002651993,0.00002894691,0.001533175],"study_design_scores_gemma":[0.00004568583,0.0005889846,0.02309807,0.00001723301,0.00003272582,0.001369868,0.00007721451,0.001054913,0.9720534,0.0002455907,0.00140701,0.000009408097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847516,0.007925143,0.005273451,0.0002268053,0.00003964181,0.0001089621,0.0002869822,0.0001054236,0.001281857],"genre_scores_gemma":[0.995415,0.00185683,0.001583349,0.00007742907,0.00001293155,0.00006669808,0.0002120168,0.000006221627,0.0007695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008646889,"threshold_uncertainty_score":0.003215909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01390108094005238,"score_gpt":0.2157815853515885,"score_spread":0.2018805044115361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}