{"id":"W1484525335","doi":"10.1186/ar1396","title":"Regulatory role of C5a anaphylatoxin on the Fcγ Rs effector system in immune complex-induced diseases","year":2004,"lang":"en","type":"article","venue":"Arthritis Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Arthritis Network; School of Medicine, University of California, San Diego; Menzies Institute for Medical Research; National Cancer Institute; Arthritis Society; University of North Carolina at Chapel Hill; Genentech; National Institutes of Health; Biogen; Lupus Research Institute; Pfizer; Natural Sciences and Engineering Research Council of Canada; Dutch Arthritis Association; Oesterreichische Nationalbank; Deutsche Forschungsgemeinschaft; Nuffield Foundation; Physiotherapy Foundation of Canada; Canadian Institutes of Health Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Lupus Research Alliance; Wellcome Trust; Newcastle University; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Austrian Science Fund; Arthritis Foundation","keywords":"Arthus reaction; Immunology; Autoantibody; Inflammation; Immune complex; Immune system; Complement system; Antibody; Chemistry; Effector; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003001957,0.0004253791,0.000269322,0.0008677738,0.000216276,0.0007323361,0.0006009867,0.0006831015,0.003515564],"category_scores_gemma":[0.0009489236,0.00009569254,0.0004384834,0.0002224989,0.0005666359,0.0004876251,0.0006662352,0.0004622357,0.0003943998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005128588,"about_ca_system_score_gemma":0.0004599381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006028457,"about_ca_topic_score_gemma":0.0002505706,"domain_scores_codex":[0.9993939,0.0002295575,0.00004187719,0.0000985496,0.000120124,0.0001159147],"domain_scores_gemma":[0.9993511,0.0002467009,0.0001596375,0.0000366841,0.0001174021,0.00008859873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00829358,0.0011322,0.0747555,0.006008219,0.0005675514,0.003955075,0.001278725,0.004131461,0.4434153,0.02126368,0.01232511,0.4228736],"study_design_scores_gemma":[0.0009895532,0.01272943,0.5543818,0.003119988,0.000807825,0.008785134,0.001631557,0.009797712,0.1318424,0.02125892,0.2545253,0.0001303582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6559469,0.3039749,0.01035502,0.007007744,0.001224327,0.0004733808,0.0007059275,0.0001640326,0.02014788],"genre_scores_gemma":[0.9459699,0.04078894,0.005401284,0.001259479,0.001246214,0.0002039953,0.0006024228,0.00001524169,0.004512492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003515564,"threshold_uncertainty_score":0.01587605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0497927475821215,"score_gpt":0.3433761407668344,"score_spread":0.2935833931847129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}