{"id":"W1485161311","doi":"10.1038/79216","title":"The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes","year":2000,"lang":"en","type":"review","venue":"Nature Genetics","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1773,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill Genome Centre; McGill University Health Centre","funders":"Wellcome Trust","keywords":"Type 2 diabetes; Population stratification; Biology; Odds ratio; Allele; Diabetes mellitus; Population; Case-control study; Peroxisome proliferator-activated receptor; Internal medicine; Genetics; Polymorphism (computer science); Allele frequency; Endocrinology; Genotype; Single-nucleotide polymorphism; Medicine; Receptor; Gene; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004443164,0.0008692002,0.001926815,0.0007893879,0.0001247519,0.0005121903,0.0007327418,0.001016036,0.001790413],"category_scores_gemma":[0.0005854478,0.0001820336,0.0003172625,0.001303791,0.0002670272,0.0003098359,0.0002635917,0.0007990535,0.0008825171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000225417,"about_ca_system_score_gemma":0.0004377298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001226559,"about_ca_topic_score_gemma":0.001570639,"domain_scores_codex":[0.9998484,0.0000257104,0.00002077357,0.00004832202,0.00004577333,0.00001105863],"domain_scores_gemma":[0.9997142,0.0001397798,0.00006301606,0.000009683661,0.00005118198,0.00002217838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0008004502,0.0000690894,0.005072356,0.006363722,0.0005464706,0.001817814,0.00003254747,0.000280372,0.004887977,0.0008230789,0.01922865,0.9600774],"study_design_scores_gemma":[0.0005158463,0.0006569946,0.05756084,0.004409598,0.002832846,0.0212753,0.0001832304,0.0003976776,0.003811139,0.004976518,0.9032882,0.00009168742],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001603373,0.9958897,0.0004978754,0.000685768,0.0003644526,0.00000318895,0.00005494702,0.00001336414,0.0008872987],"genre_scores_gemma":[0.006514133,0.9907343,0.0005275995,0.0004942676,0.000667176,0.000007644546,0.00009209926,0.00000311522,0.000959678],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001926815,"threshold_uncertainty_score":0.005989492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008651511194446432,"score_gpt":0.2648205905185894,"score_spread":0.256169079324143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}