{"id":"W1486598251","doi":"10.1111/j.1600-6143.2012.04013.x","title":"Evolution and Clinical Pathologic Correlations of De Novo Donor-Specific HLA Antibody Post Kidney Transplant","year":2012,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":928,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shared Health; University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Donor specific antibodies; Antibody; Human leukocyte antigen; Kidney; Kidney transplantation; Serology; Transplantation; Internal medicine; Gastroenterology; Pathology; Immunology; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006094521,0.0001406612,0.0002027083,0.0007518356,0.0002959269,0.000512223,0.0002354351,0.0002754455,0.001489525],"category_scores_gemma":[0.002222017,0.0001419966,0.0001702707,0.0005440849,0.0003126719,0.0004213833,0.0002882476,0.0004006105,0.0002003924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002612725,"about_ca_system_score_gemma":0.0002261847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008520209,"about_ca_topic_score_gemma":0.001063489,"domain_scores_codex":[0.9996705,0.00006661539,0.00004931822,0.00007259652,0.00006459917,0.0000764123],"domain_scores_gemma":[0.9976357,0.0005930023,0.001091348,0.0001073435,0.0001677184,0.0004048953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007008746,0.00001219213,0.9989703,0.000002018104,0.000005896383,0.0001205026,0.00001731994,0.00001479993,0.0001619113,0.00000843725,0.00001081801,0.0006057506],"study_design_scores_gemma":[0.00000271557,0.0001274352,0.9984093,0.000002224587,0.00001053178,0.001115776,0.00007239245,0.00007645985,0.0001130451,0.00001733984,0.00005111089,0.000001731364],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995447,0.0001419778,0.00003345673,0.00000682137,0.000001432037,0.000001845598,0.00003272977,0.000001499826,0.0002355499],"genre_scores_gemma":[0.9998235,0.00003996565,0.00001768702,0.000003495912,0.000004334163,0.000001266995,0.00005499833,3.751787e-7,0.00005450646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001489525,"threshold_uncertainty_score":0.004982948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02184551065478222,"score_gpt":0.3350296397160532,"score_spread":0.313184129061271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}