{"id":"W1487486460","doi":"","title":"NON-VIRAL GENE DELIVERY WITH pH-SENSITIVE GEMINI NANOPARTICLES: SYNTHESIS OF GEMINI SURFACTANT BUILDING BLOCKS, CHARACTERIZATION AND IN VITRO SCREENING OF TRANSFECTION EFFICIENCY AND TOXICITY","year":2008,"lang":"en","type":"article","venue":"University Library - University of Saskatchewan (University of Saskatchewan)","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Brookhaven National Laboratory; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Gene delivery; Transfection; Pulmonary surfactant; Chemistry; In vitro; Toxicity; Nanoparticle; Nanotechnology; Biochemistry; Gene; Materials science; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001284229,0.000247264,0.0005508745,0.0003581872,0.0002072519,0.000004628254,0.000314005,0.0002414512,0.00002047697],"category_scores_gemma":[0.000006356624,0.0003311235,0.0001439872,0.0003912587,0.0009852697,0.0002291311,0.0002810619,0.0001441804,3.06221e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002985618,"about_ca_system_score_gemma":0.0002988321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004022816,"about_ca_topic_score_gemma":0.0007318869,"domain_scores_codex":[0.9987069,0.0001079984,0.0002115619,0.0004966428,0.0002146411,0.0002622862],"domain_scores_gemma":[0.9990264,0.00006477698,0.0003618243,0.0002564709,0.0001564908,0.0001340909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003977513,0.0002058148,0.01863883,0.0001234119,0.0001734541,0.00009746163,0.02734479,0.000170339,0.9478877,7.184722e-7,0.000004747571,0.001375164],"study_design_scores_gemma":[0.001516044,0.0005188959,0.03753506,0.0001787003,0.0001465079,0.00002388859,0.1625351,0.0004282478,0.7968192,0.000001851169,0.00002091997,0.0002756163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936737,0.00005020529,0.00556788,0.00005656167,0.00001812189,0.000228733,0.0003334409,0.00001660738,0.00005478617],"genre_scores_gemma":[0.9938902,0.0006154533,0.005014434,0.0000100717,0.000009831965,2.244018e-8,0.00007955932,0.00001439181,0.0003660416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1510686,"threshold_uncertainty_score":0.9999141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004859449783810621,"score_gpt":0.1515886562865083,"score_spread":0.1467292065026977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}