{"id":"W1487843056","doi":"10.1002/9781118870914.ch6","title":"Protein Subunit Vaccine Purification","year":2014,"lang":"en","type":"other","venue":"","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Biopharmaceutical; Protein subunit; Process development; Automation; Process (computing); Product (mathematics); Biotechnology; Engineering; Computer science; Biology; Process engineering; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001705484,0.0001788511,0.0001465176,0.00005728511,0.00002505234,0.00001560729,0.0002289692,0.0003847079,0.002831449],"category_scores_gemma":[0.00007620136,0.0001592051,0.00006467658,0.00005318848,0.00002664514,5.259978e-7,0.00004235365,0.00008291782,0.000436386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007259289,"about_ca_system_score_gemma":0.00004585353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004378283,"about_ca_topic_score_gemma":0.0001368822,"domain_scores_codex":[0.9991006,0.00007600612,0.0001693436,0.0004116585,0.0001002423,0.0001422023],"domain_scores_gemma":[0.9989049,0.000001704377,0.0001345792,0.0008461357,0.00004667467,0.000066027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003721966,0.0001169845,0.0001423567,0.0001282744,0.00006394659,3.029613e-7,0.000003946485,2.712362e-7,0.1489598,0.003615908,0.8355073,0.01142364],"study_design_scores_gemma":[0.0001987144,0.00005130781,0.0001620687,0.00001367879,0.000006474077,0.000001014334,0.000002623457,0.000005255969,0.03229889,0.00006545227,0.9670001,0.0001944855],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.0003419423,0.001682361,0.01593579,0.0004661575,0.00009798235,0.001068052,0.00003200188,0.0001376141,0.9802381],"genre_scores_gemma":[0.02273632,0.000098911,0.001719662,0.0001729037,0.0004162708,0.0001853255,0.0006657147,0.0002028961,0.973802],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.1314927,"threshold_uncertainty_score":0.9980801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007867023304131752,"score_gpt":0.2360442324560338,"score_spread":0.2281772091519021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}