{"id":"W1487942294","doi":"10.5772/15058","title":"Effective Derivation and Manipulation of Mouse Embryonic Stem Cells","year":2011,"lang":"en","type":"book-chapter","venue":"InTech eBooks","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China; University of Calgary","keywords":"Inner cell mass; Epiblast; Embryonic stem cell; Blastocyst; Cell biology; Biology; Stem cell; Embryoid body; Embryo; Immunology; Adult stem cell; Embryogenesis; Genetics; Gene; Gastrulation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005377849,0.0006448384,0.0006457194,0.001217497,0.000391848,0.0007849169,0.0007068106,0.0005453746,0.005786808],"category_scores_gemma":[0.0003406235,0.000517269,0.0004544114,0.001036241,0.0002987128,0.0006180677,0.000806781,0.001613574,0.01082303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003323951,"about_ca_system_score_gemma":0.0005109924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00043146,"about_ca_topic_score_gemma":0.0009329906,"domain_scores_codex":[0.9995431,0.0000345585,0.00004398284,0.00006059332,0.000282457,0.00003532099],"domain_scores_gemma":[0.9999206,0.00001632928,0.000009566376,0.00002238118,0.00002031644,0.00001087832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003824733,0.0000340222,0.0001133601,0.0005682362,0.00001657994,0.0002962081,0.00009629474,0.0004710545,0.8763908,0.009969927,0.01052067,0.1014845],"study_design_scores_gemma":[0.00001898033,0.00007435906,0.001349564,0.0002026155,0.00004084201,0.001101029,0.00002803097,0.0007799213,0.3948147,0.003942405,0.5976174,0.00003019199],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.04887832,0.1122946,0.6443373,0.001930707,0.0025968,0.001424368,0.0188135,0.007444401,0.16228],"genre_scores_gemma":[0.1223416,0.1369513,0.5208531,0.001842367,0.0004831358,0.002146357,0.02832654,0.001964984,0.1850906],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.005786808,"threshold_uncertainty_score":0.01935881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02205604666954709,"score_gpt":0.2428409420979168,"score_spread":0.2207848954283698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}