{"id":"W1487996345","doi":"10.1038/npg.els.0006101","title":"Antitrypsin ( <scp>AAT</scp> ) Deficiency‐α <sub>1</sub>","year":2006,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Alpha 1-antitrypsin deficiency; Pulmonary disease; Mutation; Disease; Gene; Medicine; Biology; Immunology; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003863461,0.0003679263,0.0003785855,0.0002502242,0.0001260606,0.00002843367,0.0007491458,0.0004704532,0.00002977806],"category_scores_gemma":[0.0003972815,0.0003247173,0.000183739,0.000375489,0.000555074,0.000008721557,0.0002158058,0.0001420005,0.00007068558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008058925,"about_ca_system_score_gemma":0.0005473617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001646534,"about_ca_topic_score_gemma":0.0001521182,"domain_scores_codex":[0.9976667,0.0000797964,0.0003986544,0.0007792495,0.0005609227,0.0005146699],"domain_scores_gemma":[0.9988551,0.00002828976,0.0004420299,0.0004653888,0.00005451263,0.0001546791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000001687544,0.00008219092,0.0006998255,0.00005922439,0.00001480002,0.000002504201,0.0000117728,0.00000826594,0.1877415,0.0002143844,0.8106095,0.0005542872],"study_design_scores_gemma":[0.0002012576,0.0003243765,0.00009078322,0.00009818927,0.00002555312,0.000004484725,0.0000526797,0.000007324094,0.3673006,0.0002445888,0.6314541,0.0001960412],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.08485629,0.01623606,0.0004287261,0.0000257493,0.00112999,0.0003655425,0.0001179573,0.00005910878,0.8967806],"genre_scores_gemma":[0.2805465,0.03511041,0.01110419,0.001296838,0.01142532,0.0002098638,0.0006929594,0.001067673,0.6585463],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.2382343,"threshold_uncertainty_score":0.9999205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007481313964905848,"score_gpt":0.2234460271590114,"score_spread":0.2159647131941056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}