{"id":"W1487996345","doi":"10.1038/npg.els.0006101","title":"Antitrypsin ( <scp>AAT</scp> ) Deficiency‐α <sub>1</sub>","year":2006,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Alpha 1-antitrypsin deficiency; Pulmonary disease; Mutation; Disease; Gene; Medicine; Biology; Immunology; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001999719,0.0008656378,0.0004398614,0.001781073,0.0002512067,0.001147581,0.0004979721,0.0003720866,0.07943428],"category_scores_gemma":[0.0004450517,0.00008650014,0.0002226423,0.001694037,0.0001862254,0.0005351244,0.000611077,0.0004165274,0.05302093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002982628,"about_ca_system_score_gemma":0.0003342155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008058037,"about_ca_topic_score_gemma":0.001151721,"domain_scores_codex":[0.9998734,0.00001765748,0.00001404338,0.0000145369,0.00005535997,0.0000250483],"domain_scores_gemma":[0.9998531,0.00003404638,0.00002819225,0.00001766479,0.00003084606,0.0000360216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004312445,0.0002660938,0.004413278,0.001393801,0.00004051462,0.006589221,0.00006235881,0.0001647055,0.0162521,0.0055886,0.1485936,0.8162044],"study_design_scores_gemma":[0.00003711662,0.00007422061,0.008216216,0.0004417386,0.00004395333,0.02674821,0.00004992587,0.0002063635,0.006954972,0.002185422,0.9550278,0.00001402865],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.04502542,0.1948197,0.01299068,0.002586843,0.002053806,0.0002966326,0.01295364,0.003196563,0.7260767],"genre_scores_gemma":[0.1316238,0.1555944,0.01553685,0.001296143,0.0007992474,0.0001748618,0.01536463,0.0004959087,0.6791142],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.07943428,"threshold_uncertainty_score":0.2657341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007481313964905848,"score_gpt":0.2234460271590114,"score_spread":0.2159647131941056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}