{"id":"W1488289517","doi":"","title":"The RPGRIP1-deficient dog, a promising canine model for gene therapy.","year":2009,"lang":"en","type":"preprint","venue":"PubMed","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Outer nuclear layer; TUNEL assay; Electroretinography; Retina; Retinal; Erg; Ophthalmology; Histopathology; Fundus (uterus); Retinal degeneration; Genetic enhancement; Biology; H&E stain; Medicine; Pathology; Anatomy; Staining; Gene; Neuroscience; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004724938,0.0002560484,0.0001746881,0.00003025318,0.0001901319,0.000116158,0.0003924994,0.0002409864,7.284427e-7],"category_scores_gemma":[0.00008513935,0.0001819428,0.0001838055,0.0000376608,0.00005325401,0.000001241515,0.0002205753,0.0001384583,6.605197e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003290288,"about_ca_system_score_gemma":0.0002161308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001287295,"about_ca_topic_score_gemma":0.0000289431,"domain_scores_codex":[0.9985765,0.00003151464,0.0002580085,0.0004917046,0.000161818,0.000480519],"domain_scores_gemma":[0.9992172,0.00001177143,0.0001491234,0.0004295164,0.0001096708,0.00008278133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001491722,0.0003684439,0.000950166,0.0001594214,0.0005966107,0.000003179874,0.0004848521,0.02526724,0.02680752,0.0004308936,0.03288475,0.9105552],"study_design_scores_gemma":[0.01006318,0.0005757273,0.103402,0.0001205806,0.0003289913,0.00003429213,0.0002565512,0.06463329,0.2763379,0.04323481,0.4956585,0.00535416],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9362349,0.02042457,0.02754547,0.002846347,0.0008020504,0.006420353,0.000079729,0.00005713953,0.00558947],"genre_scores_gemma":[0.9798675,0.004544304,0.002328146,0.0006262584,0.0003196446,0.005823466,0.0005193035,0.00005066799,0.005920708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.905201,"threshold_uncertainty_score":0.7419412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02821837243746018,"score_gpt":0.246852321987829,"score_spread":0.2186339495503688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}