{"id":"W1488501687","doi":"10.18632/oncotarget.933","title":"Gfi1 as a regulator of p53 and a therapeutic target for ALL","year":2013,"lang":"en","type":"article","venue":"Oncotarget","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal","funders":"","keywords":"Regulator; Cancer research; Repressor; Negative regulator; Leukemia; Cancer; Lymphoblastic Leukemia; Biology; Transcriptional regulation; Computational biology; Medicine; Transcription factor; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003870543,0.0001021958,0.0001256482,0.00001555675,0.00002761217,0.000009936354,0.00006404438,0.00008494974,0.00006312096],"category_scores_gemma":[0.00001342089,0.00008434457,0.00006159625,0.00002252113,0.0000433176,0.000002334945,0.0000312849,0.00001949815,0.00001042701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002938354,"about_ca_system_score_gemma":0.00002914417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000601897,"about_ca_topic_score_gemma":0.000007534688,"domain_scores_codex":[0.9994814,0.00001326656,0.0001101437,0.0001911803,0.00005144811,0.000152541],"domain_scores_gemma":[0.9996608,0.000007474207,0.00005012211,0.0001731776,0.00005061099,0.00005776115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003714432,0.001121743,0.1144051,0.0001547143,0.00129376,0.00000291891,0.0003312504,0.0000126492,0.8247788,0.002591986,0.03298704,0.02194859],"study_design_scores_gemma":[0.006796873,0.004214864,0.02675019,0.00002554722,0.0001932845,0.00002841488,0.0002079367,0.0003431439,0.4795144,0.0341525,0.4471586,0.0006141709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944108,0.003542459,0.0001990634,0.0003754166,0.00004320273,0.0003685296,0.00002386058,0.000005555117,0.001031103],"genre_scores_gemma":[0.9947717,0.00009055695,0.003183916,0.0005008774,0.00004243228,0.00009508845,0.00008538468,0.00001727664,0.001212738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4141716,"threshold_uncertainty_score":0.3439472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006773031813727053,"score_gpt":0.2482212228589854,"score_spread":0.2414481910452584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}