{"id":"W1488501687","doi":"10.18632/oncotarget.933","title":"Gfi1 as a regulator of p53 and a therapeutic target for ALL","year":2013,"lang":"en","type":"article","venue":"Oncotarget","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal","funders":"","keywords":"Regulator; Cancer research; Repressor; Negative regulator; Leukemia; Cancer; Lymphoblastic Leukemia; Biology; Transcriptional regulation; Computational biology; Medicine; Transcription factor; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001893394,0.0001963852,0.0002134434,0.0003617614,0.0001606902,0.0003899108,0.0002119066,0.0003367121,0.001206059],"category_scores_gemma":[0.00008265284,0.00007035839,0.0001836577,0.0002205986,0.0002690722,0.0002403116,0.0002098317,0.0008022697,0.0002859105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004448892,"about_ca_system_score_gemma":0.0002778507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002723405,"about_ca_topic_score_gemma":0.0007042688,"domain_scores_codex":[0.9999448,0.00001034187,0.000002214781,0.000006976715,0.00001936707,0.00001624727],"domain_scores_gemma":[0.9999776,0.000003722538,0.000005706931,0.000002443144,0.000003651154,0.000006858028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001357015,0.0003743279,0.001191885,0.0004259681,0.00003393963,0.0009752302,0.00008870859,0.0009713143,0.8062419,0.009185057,0.005411213,0.1737434],"study_design_scores_gemma":[0.0006414701,0.005254404,0.01154511,0.0001313802,0.0001875651,0.005086283,0.0001439313,0.002212059,0.7099629,0.004892839,0.2599042,0.00003792008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7795635,0.1589433,0.008388148,0.01147416,0.0007324343,0.0001826267,0.0005519011,0.0004846787,0.03967938],"genre_scores_gemma":[0.9485407,0.03710153,0.003330418,0.001037336,0.0001652126,0.00007104586,0.0003434425,0.00003113681,0.009379163],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001206059,"threshold_uncertainty_score":0.004034698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006773031813727053,"score_gpt":0.2482212228589854,"score_spread":0.2414481910452584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}