{"id":"W1488835948","doi":"10.1038/nrc1047","title":"Improving the evaluation of new cancer treatments: challenges and opportunities","year":2003,"lang":"en","type":"review","venue":"Nature reviews. Cancer","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":149,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Cancer Institute; McGill University","keywords":"Clinical trial; Medicine; Cancer; Cancer drugs; Intensive care medicine; Computational biology; Biology; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.01327794,0.001671155,0.005595669,0.004180157,0.0006506088,0.003921324,0.002696715,0.004176883,0.004924721],"category_scores_gemma":[0.0177296,0.0006449352,0.001368692,0.006099311,0.002241413,0.005495291,0.001835752,0.00448662,0.002123015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002993476,"about_ca_system_score_gemma":0.007072262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004063012,"about_ca_topic_score_gemma":0.009449077,"domain_scores_codex":[0.995353,0.002320282,0.0004837313,0.0002640509,0.001415626,0.0001632748],"domain_scores_gemma":[0.976162,0.01777361,0.001173979,0.0003862787,0.00393476,0.0005693168],"domain_codex":null,"domain_gemma":"evaluation","domain_candidate":"evaluation","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001357876,0.00008247282,0.0002482252,0.01979664,0.0001751022,0.00009133221,0.00008459391,0.0003694306,0.0004620603,0.005031717,0.03468785,0.9388347],"study_design_scores_gemma":[0.0001412048,0.0002666845,0.001905268,0.03267015,0.0006219555,0.0009766163,0.0005371221,0.0002570071,0.000517295,0.01338523,0.9486631,0.0000583068],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003953592,0.9968836,0.0001578474,0.002215231,0.0002550084,0.000005215998,0.000007224202,0.000003957604,0.0004323995],"genre_scores_gemma":[0.0003673736,0.9983381,0.0003349266,0.0005295745,0.0003039112,0.000008412521,0.000008193012,0.000001140641,0.0001083617],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9867221,"threshold_uncertainty_score":0.07022136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3441167785904543,"score_gpt":0.471561718432465,"score_spread":0.1274449398420108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}