{"id":"W1489237778","doi":"10.1046/j.1365-2958.2001.02539.x","title":"Structure, activity and evolution of the group I thiolactone peptide quorum‐sensing system of<i>Staphylococcus aureus</i>","year":2001,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":186,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council","keywords":"Quorum sensing; Biology; Staphylococcus aureus; Amino acid; Alanine; Peptide sequence; Virulence; Peptide; Tyrosine; Biochemistry; Microbiology; Bacteria; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009075574,0.0001486336,0.0001118189,0.00009381252,0.00006196233,0.0002258132,0.0001447512,0.0001289292,0.0003697762],"category_scores_gemma":[0.0001384907,0.00006119735,0.000130014,0.00008377973,0.0001167464,0.00008352877,0.00007402151,0.0001939256,0.0001863553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002463813,"about_ca_system_score_gemma":0.0001311187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007386844,"about_ca_topic_score_gemma":0.0004426822,"domain_scores_codex":[0.9999242,0.0000158325,0.000006887366,0.00001268441,0.00002761112,0.00001270737],"domain_scores_gemma":[0.9999185,0.00001542627,0.00002802227,0.000009514767,0.00001241729,0.00001623915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004069407,0.000008115831,0.0003564306,0.000007769865,0.000001360014,0.00001920458,0.000008194194,0.00009156121,0.9988403,0.00002903266,0.000004043567,0.0005933659],"study_design_scores_gemma":[0.00001006178,0.0005577588,0.01389664,0.000003656032,0.00001405782,0.0002766255,0.00003332446,0.001195408,0.9831458,0.00003272363,0.0008274646,0.000006367664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991591,0.0001563045,0.000256713,0.00001562743,0.000001515582,0.000003907469,0.00004866578,0.000005060601,0.0003530162],"genre_scores_gemma":[0.9986672,0.00009115176,0.0006180021,0.00001281697,0.000002362613,0.000003883843,0.0002584928,0.000003974619,0.000342135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007386844,"threshold_uncertainty_score":0.001787603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00519813021947116,"score_gpt":0.218092174311204,"score_spread":0.2128940440917329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}