{"id":"W1489237778","doi":"10.1046/j.1365-2958.2001.02539.x","title":"Structure, activity and evolution of the group I thiolactone peptide quorum‐sensing system of<i>Staphylococcus aureus</i>","year":2001,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":186,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council","keywords":"Quorum sensing; Biology; Staphylococcus aureus; Amino acid; Alanine; Peptide sequence; Virulence; Peptide; Tyrosine; Biochemistry; Microbiology; Bacteria; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000183193,0.0002444221,0.0006038508,0.0001267207,0.0000866641,0.000005921723,0.0001642792,0.0002796675,0.000007189367],"category_scores_gemma":[0.0000970517,0.0001815778,0.0002007043,0.0003610951,0.0005603115,0.00003538494,0.0001569683,0.0003034871,0.000001678403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001818651,"about_ca_system_score_gemma":0.0001012316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002709387,"about_ca_topic_score_gemma":0.000119498,"domain_scores_codex":[0.9985217,0.0002390684,0.0003979374,0.0003811318,0.0001024533,0.0003577359],"domain_scores_gemma":[0.998722,0.00007061326,0.0003753588,0.0005893128,0.0001786,0.00006413217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003747228,0.00004550427,0.01246845,0.0002572222,0.0001168079,0.00003690913,0.0000567528,0.00001211449,0.9852469,0.000874706,0.000129151,0.0003807544],"study_design_scores_gemma":[0.001102195,0.0001847983,0.05130396,0.0003613812,0.0001878743,0.0004485871,0.0001381905,0.00003580078,0.9448342,0.0000756309,0.001142667,0.0001846844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991912,0.001253554,0.005335434,0.0001692177,0.0001978113,0.0005813062,0.00008221982,0.00003412615,0.0004343435],"genre_scores_gemma":[0.9987636,0.00002486473,0.0009628908,0.0001244969,0.00003668347,0.000001594175,0.00001304052,0.00003002392,0.0000428121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04041267,"threshold_uncertainty_score":0.7404528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00519813021947116,"score_gpt":0.218092174311204,"score_spread":0.2128940440917329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}