{"id":"W1489293801","doi":"10.4049/jimmunol.188.supp.113.34","title":"IL-2 and IL-6 cooperate to enhance the generation of effectors from aged human CD8 T cells to live influenza virus (113.34)","year":2012,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research & Development Corporation; Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"","keywords":"Cytotoxic T cell; Immunology; CD8; Cytolysis; Biology; CTL*; Peripheral blood mononuclear cell; Effector; Interleukin 21; Granzyme; Granzyme B; Granzyme A; Virology; Immune system; Perforin; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002065402,0.0004237181,0.0002674767,0.0001298802,0.00007137823,0.0002123208,0.0001137325,0.0002130175,0.001630998],"category_scores_gemma":[0.0001553454,0.0001593211,0.000256602,0.00004395036,0.0001014914,0.0001233416,0.0002039364,0.0003926346,0.0006033991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008227294,"about_ca_system_score_gemma":0.00008041202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001439049,"about_ca_topic_score_gemma":0.0004072545,"domain_scores_codex":[0.9999059,0.00002025068,0.00001015475,0.00002308491,0.00001394066,0.00002667075],"domain_scores_gemma":[0.9998837,0.00001274622,0.00002078647,0.00001227422,0.00001096242,0.00005964094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000453068,0.00009486367,0.0007843248,0.00005517709,0.000007890862,0.00008572001,0.00002345337,0.00005552982,0.996097,0.00003096488,0.00007793537,0.002234094],"study_design_scores_gemma":[0.0004083851,0.009936277,0.08352029,0.00005624913,0.0001500589,0.001917947,0.0001024405,0.001422253,0.8876753,0.0001365571,0.01465734,0.00001699122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952113,0.002291541,0.00112207,0.00008093462,0.00007506103,0.00003687078,0.0001970368,0.00004072048,0.0009443408],"genre_scores_gemma":[0.9928142,0.0007812737,0.001733132,0.0001502373,0.0001085334,0.00004960093,0.0005126353,0.00001205498,0.00383826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001630998,"threshold_uncertainty_score":0.005456209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01851123405071942,"score_gpt":0.2697160800537536,"score_spread":0.2512048460030342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}