{"id":"W1489615041","doi":"10.4049/jimmunol.181.3.1700","title":"IFN-γ Induces the Erosion of Preexisting CD8 T Cell Memory during Infection with a Heterologous Intracellular Bacterium","year":2008,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Institute for Biological Sciences","funders":"Canadian Institutes of Health Research","keywords":"Biology; Heterologous; Intracellular; Intracellular parasite; Cytotoxic T cell; CD8; Microbiology; Pathogen; T cell; Listeria monocytogenes; Immunology; Cell biology; Immune system; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001480587,0.0005974572,0.0004270912,0.0001273703,0.0001100211,0.0002782943,0.0002189576,0.000348899,0.0007968483],"category_scores_gemma":[0.0002027135,0.0001625102,0.0002922581,0.00009941175,0.0003050626,0.0002023332,0.0002650296,0.001340011,0.0003031156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003703382,"about_ca_system_score_gemma":0.0001941084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003948187,"about_ca_topic_score_gemma":0.0005367233,"domain_scores_codex":[0.9998212,0.00002489846,0.0000191856,0.00003859553,0.00002317781,0.00007302733],"domain_scores_gemma":[0.999836,0.00003034891,0.00004228285,0.00003839049,0.00001575383,0.00003719398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003800333,0.00006870039,0.0003342563,0.00005275511,0.000006476114,0.0001100788,0.00004322891,0.00008700676,0.9964935,0.00003780603,0.00003705172,0.002348954],"study_design_scores_gemma":[0.00007888329,0.001132738,0.009349884,0.00003659371,0.00003547304,0.0003934656,0.00009722308,0.001009342,0.9855064,0.0001070126,0.002245574,0.00000736015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997071,0.001115656,0.0007457791,0.00004990475,0.00003615472,0.00002172089,0.00009038005,0.00004446691,0.0008249293],"genre_scores_gemma":[0.9954566,0.0007537781,0.001000819,0.0001334545,0.00002280543,0.00003818011,0.0002721324,0.00001521846,0.002307014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007968483,"threshold_uncertainty_score":0.002686977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0119146033406486,"score_gpt":0.1966593657154794,"score_spread":0.1847447623748308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}