{"id":"W1489773117","doi":"10.4049/jimmunol.192.supp.50.11","title":"Unique progenitors in adult mouse bone marrow expressing CD127 (IL-7Rα) and high level of cKit efficiently develop into all lymphocytes including T cells and innate lymphoid cells (HEM2P.266)","year":2014,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency","funders":"","keywords":"Interleukin-7 receptor; Progenitor cell; Innate lymphoid cell; Biology; Lymphopoiesis; Bone marrow; Immunology; Myeloid; Population; Cell biology; Stem cell; T cell; Innate immune system; Immune system; IL-2 receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001598042,0.000347663,0.0008113058,0.0004451909,0.0002664878,0.00002295103,0.0004870866,0.0004538434,0.00001352815],"category_scores_gemma":[0.000345882,0.0002563169,0.00007040887,0.000274823,0.0008543914,0.0001963752,0.0004308602,0.0005633947,0.00001409521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001617258,"about_ca_system_score_gemma":0.0002947604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005268786,"about_ca_topic_score_gemma":0.00009851658,"domain_scores_codex":[0.9969936,0.001044142,0.001058712,0.0002586175,0.00008729604,0.0005576592],"domain_scores_gemma":[0.9976494,0.0006234622,0.0009409422,0.0003127649,0.0004296223,0.00004383831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009126756,0.0001391265,0.000939325,0.00007413444,0.0002452788,0.00001267456,0.006333396,0.00003984665,0.9863532,0.0002605588,0.0001534333,0.004536356],"study_design_scores_gemma":[0.004059443,0.0005893314,0.001539976,0.0002181071,0.00008679982,0.0009750641,0.001196558,0.00002525583,0.987923,0.0003760581,0.002740135,0.0002702551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944915,0.003701088,0.0005557921,0.0001656974,0.0007058099,0.0002074947,0.00008925181,0.00001908815,0.00006424387],"genre_scores_gemma":[0.995447,0.002889531,0.001200041,0.0001757927,0.00004477249,0.000004826313,0.000009606885,0.00003666039,0.0001917576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005136839,"threshold_uncertainty_score":0.9999889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02166750317661928,"score_gpt":0.2315745504272127,"score_spread":0.2099070472505934,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}