{"id":"W1489773117","doi":"10.4049/jimmunol.192.supp.50.11","title":"Unique progenitors in adult mouse bone marrow expressing CD127 (IL-7Rα) and high level of cKit efficiently develop into all lymphocytes including T cells and innate lymphoid cells (HEM2P.266)","year":2014,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency","funders":"","keywords":"Interleukin-7 receptor; Progenitor cell; Innate lymphoid cell; Biology; Lymphopoiesis; Bone marrow; Immunology; Myeloid; Population; Cell biology; Stem cell; T cell; Innate immune system; Immune system; IL-2 receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001189921,0.0004091154,0.0001659625,0.0004807072,0.0001430338,0.0002512675,0.0001688895,0.0002618917,0.001604457],"category_scores_gemma":[0.00006559562,0.00021573,0.0001603767,0.0001290385,0.0001593524,0.0001590403,0.0002902646,0.0008047336,0.000685969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001672738,"about_ca_system_score_gemma":0.000134322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002571925,"about_ca_topic_score_gemma":0.0005192304,"domain_scores_codex":[0.9998537,0.00001118819,0.00001455394,0.00003135641,0.00004920698,0.00003990543],"domain_scores_gemma":[0.9998322,0.00001215604,0.00004646157,0.00001736278,0.00001094407,0.00008079514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005714434,0.0000117534,0.0001824325,0.00001255193,0.000001805079,0.00004262581,0.00001068734,0.00002775154,0.9987218,0.00007341168,0.00002398553,0.0008339826],"study_design_scores_gemma":[0.00003612044,0.000281531,0.00688933,0.00001368824,0.00001619097,0.0005124407,0.00002284314,0.0006011256,0.9890186,0.0000708746,0.002532959,0.000004456475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901574,0.001250607,0.004743951,0.00005025046,0.00001619692,0.00007361523,0.001051891,0.0002782035,0.002377936],"genre_scores_gemma":[0.9857237,0.0005767256,0.00414435,0.00004514581,0.00001190838,0.0001154822,0.001898814,0.00009771901,0.007386154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001604457,"threshold_uncertainty_score":0.005367458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02166750317661928,"score_gpt":0.2315745504272127,"score_spread":0.2099070472505934,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}