{"id":"W1489813003","doi":"10.1155/2010/578432","title":"Archaeosome Adjuvant Overcomes Tolerance to Tumor‐Associated Melanoma Antigens Inducing Protective CD8<sup>+</sup> T Cell Responses","year":2010,"lang":"en","type":"article","venue":"Journal of Immunology Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"Government of Ontario; Ontario Institute for Cancer Research","keywords":"Antigen; Adjuvant; CD8; Priming (agriculture); Cytotoxic T cell; Melanoma; Immunology; Biology; T cell; Cancer research; Immune system; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008005265,0.0001937399,0.0001292971,0.00009002267,0.00007018262,0.0001666078,0.00008712848,0.0001665965,0.0006771168],"category_scores_gemma":[0.00009454382,0.00008094842,0.00009959298,0.00004326991,0.0001352657,0.00011807,0.0001829459,0.0003313734,0.0001762853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008852745,"about_ca_system_score_gemma":0.0001744497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001819288,"about_ca_topic_score_gemma":0.0003736303,"domain_scores_codex":[0.9999533,0.00001130158,0.000003753013,0.000006468875,0.00001022419,0.00001495163],"domain_scores_gemma":[0.999952,0.000007122787,0.00001284122,0.000006275966,0.000005740321,0.00001600101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002814521,0.00004266985,0.0002663851,0.00003240648,0.000003244859,0.00003241266,0.000008446499,0.00008472773,0.996883,0.00006625862,0.00002322206,0.002275812],"study_design_scores_gemma":[0.0000416078,0.001795676,0.001866694,0.00000769148,0.000018353,0.0002156986,0.00002286295,0.0006416204,0.9927037,0.0000534743,0.002629297,0.000003296101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982292,0.000507348,0.0007312852,0.00003206732,0.00001232927,0.000009766904,0.00002947637,0.00001821784,0.0004303313],"genre_scores_gemma":[0.9974014,0.0003697125,0.0009953588,0.00002343437,0.000007184706,0.000007742042,0.000101789,0.000008218536,0.001085235],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006771168,"threshold_uncertainty_score":0.002265155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0268234269672162,"score_gpt":0.3123844646861183,"score_spread":0.2855610377189021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}