{"id":"W1490339331","doi":"10.1111/ajt.12543","title":"De Novo Sirolimus and Reduced-Dose Tacrolimus Versus Standard-Dose Tacrolimus After Liver Transplantation: The 2000–2003 Phase II Prospective Randomized Trial","year":2014,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Organ Transplantation Techniques and Outcomes","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Wyeth; Pfizer","keywords":"Tacrolimus; Medicine; Sirolimus; Liver transplantation; Urology; Transplantation; Sepsis; Gastroenterology; Trough level; Adverse effect; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004381802,0.00172409,0.003122259,0.0004957353,0.0003952734,0.001760828,0.00113792,0.001807212,0.003821493],"category_scores_gemma":[0.002926694,0.0006643698,0.002679355,0.0006005229,0.001032008,0.0009596011,0.0003863254,0.003033367,0.0007249746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009012397,"about_ca_system_score_gemma":0.001421267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001020916,"about_ca_topic_score_gemma":0.001600672,"domain_scores_codex":[0.9985133,0.0009604351,0.0001142652,0.000193772,0.0001066557,0.0001115927],"domain_scores_gemma":[0.9978538,0.0007028772,0.0006329133,0.000175691,0.000137128,0.0004974607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9868515,0.002625239,0.0004773127,0.000321647,0.0009907038,0.00002596735,0.00002823687,0.0001439207,0.001282429,0.00007113693,0.0003269226,0.006855033],"study_design_scores_gemma":[0.9689571,0.02803238,0.001226723,0.00003686377,0.0006902129,0.00002996192,0.00001071407,0.0002840648,0.0002570382,0.0000666375,0.0003987118,0.000009594056],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984177,0.008652356,0.0008354142,0.001073512,0.0007726443,0.002078622,0.0007658665,0.000116511,0.00152812],"genre_scores_gemma":[0.9838574,0.004423456,0.002218765,0.002010976,0.0009761165,0.002823477,0.001392207,0.00003877204,0.002258805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004381802,"threshold_uncertainty_score":0.02317345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00844759553651486,"score_gpt":0.2895945418956992,"score_spread":0.2811469463591843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}