{"id":"W1490621183","doi":"10.1038/nn911","title":"Development of normal retinal organization depends on Sonic hedgehog signaling from ganglion cells","year":2002,"lang":"en","type":"article","venue":"Nature Neuroscience","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":150,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Retina; Laminar organization; Neuroscience; Biology; Sonic hedgehog; Intrinsically photosensitive retinal ganglion cells; Giant retinal ganglion cells; Retinal; Retinal pigment epithelium; Cell biology; Interneuron; Ganglion; Hedgehog; Anatomy; Parasol cell; Retinal ganglion cell; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008989098,0.000118895,0.0000810272,0.00005267883,0.0001240397,0.00002280563,0.0002482897,0.0001601178,0.00005700946],"category_scores_gemma":[0.0001407702,0.0001104416,0.0000261505,0.0003058884,0.00005209765,0.000007487976,0.00007275979,0.0001597587,0.00001364774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001059548,"about_ca_system_score_gemma":0.00005106911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.540048e-7,"about_ca_topic_score_gemma":0.000002862954,"domain_scores_codex":[0.9989876,0.00002429905,0.0001750307,0.0003504473,0.0002810413,0.0001815619],"domain_scores_gemma":[0.9996124,0.000009779704,0.00009422271,0.0001493489,0.00008151707,0.00005271344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002209346,0.00004662509,0.001757278,0.000005064475,0.000001521089,0.000002689983,0.0001037185,0.00007692814,0.9963044,0.00001683207,0.0004302512,0.001232595],"study_design_scores_gemma":[0.0001902563,0.00008527056,0.01065145,0.00001496072,0.000003266898,0.00000253087,0.00002452672,0.0001077508,0.9823763,0.000006360916,0.00640384,0.000133489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972362,0.0001485291,0.001116614,0.00005847386,0.0003342529,0.00006853767,0.000003619772,0.00001156733,0.001022242],"genre_scores_gemma":[0.9968722,0.0000528313,0.0022081,0.0005256026,0.00004475402,0.000001607096,0.00003239004,0.00001201386,0.0002505378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01392811,"threshold_uncertainty_score":0.4503678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008075806706035426,"score_gpt":0.2146138412720893,"score_spread":0.2065380345660539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}