{"id":"W1492167537","doi":"10.1111/bph.13102","title":"Pharmacological methyl group donors block skeletal metastasis <i>in vitro</i> and <i>in vivo</i>","year":2015,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Metastasis; DNA methylation; Cancer research; Cell growth; Biology; Methylation; In vivo; STAT3; Prostate cancer; Cell migration; Cell; Cancer; Pathology; Signal transduction; Cell biology; Medicine; Gene expression; DNA; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002075148,0.0001840847,0.0007781252,0.0004664952,0.00003961005,0.00003529831,0.0002052472,0.0001636912,0.0003224277],"category_scores_gemma":[0.0001495886,0.0001806418,0.0001557935,0.0004848325,0.0002345764,0.0002455706,0.0001225249,0.001183917,0.000009837196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001851275,"about_ca_system_score_gemma":0.0002325252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001899364,"about_ca_topic_score_gemma":0.00007548321,"domain_scores_codex":[0.9974007,0.0005229228,0.0007568556,0.0002801174,0.0004579857,0.0005814095],"domain_scores_gemma":[0.9988117,0.000207231,0.0001819204,0.00004852714,0.000229353,0.0005212185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002659479,0.001149049,0.001726595,0.00005057908,0.0002908539,0.02775856,0.0001118841,0.00002979237,0.9170136,0.000002279342,0.02751424,0.02169304],"study_design_scores_gemma":[0.06442837,0.004372661,0.01185569,0.0002400703,0.00133451,0.09645816,0.0008245575,0.001015427,0.7453681,0.0001676583,0.07322811,0.0007067147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862347,0.01054632,0.00001121744,0.001618044,0.0004974435,0.0003245968,0.00002024167,0.00001171118,0.0007356863],"genre_scores_gemma":[0.9916815,0.005007373,0.0009515156,0.001704142,0.0004425682,0.00001481405,0.000003107356,0.00002361393,0.000171414],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1716456,"threshold_uncertainty_score":0.7366359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03377950232698902,"score_gpt":0.3429087423999952,"score_spread":0.3091292400730062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}