{"id":"W1492457074","doi":"10.1161/circ.130.suppl_2.11607","title":"Abstract 11607: Novel Assay for Detection of LDL Transcytosis Across Coronary Endothelium Reveals an Unexpected Role for SR-B1","year":2014,"lang":"en","type":"article","venue":"Circulation","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Hospital for Sick Children; Toronto General Hospital; St. Michael's Hospital; University of Toronto","funders":"","keywords":"Transcytosis; Endothelium; Medicine; Cell biology; Intracellular; Internal medicine; Biology; Endocytosis; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008135988,0.001186167,0.0008363927,0.0009005397,0.0004353126,0.0007107632,0.0008476598,0.001439372,0.003925254],"category_scores_gemma":[0.0006385013,0.000346699,0.0003998166,0.0007663275,0.000382154,0.0005317331,0.0004419791,0.001491703,0.002422825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003724461,"about_ca_system_score_gemma":0.0004326779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003231415,"about_ca_topic_score_gemma":0.0004475061,"domain_scores_codex":[0.9987931,0.0003506777,0.0001025025,0.0002785895,0.0003729237,0.0001021657],"domain_scores_gemma":[0.9993033,0.000259907,0.0001091841,0.00008465363,0.0001511351,0.00009168695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009410967,0.0000498963,0.0002317703,0.0001152742,0.00001089156,0.00004282907,0.00001727484,0.00001814163,0.9959454,0.0001240687,0.0002341267,0.003116142],"study_design_scores_gemma":[0.00003036787,0.0004521399,0.005337978,0.00002682492,0.00004512643,0.0008847185,0.00001861911,0.002134368,0.9878682,0.000114193,0.00307298,0.00001449524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7364112,0.02270994,0.2204313,0.001664768,0.0006413026,0.0004530961,0.002408214,0.001882509,0.01339758],"genre_scores_gemma":[0.7432825,0.008841364,0.2213898,0.0008890798,0.0002358234,0.0008123267,0.008014472,0.000307498,0.01622719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003925254,"threshold_uncertainty_score":0.01313132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01515007022205591,"score_gpt":0.2656788520826129,"score_spread":0.250528781860557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}