{"id":"W1492486416","doi":"10.1111/j.1558-5646.2009.00942.x","title":"THE ANIMAL WITHIN: CARCINOGENESIS AND THE CLONAL EVOLUTION OF CANCER CELLS ARE SPECIATION EVENTS SENSU STRICTO","year":2009,"lang":"en","type":"article","venue":"Evolution","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Biology; Genetic algorithm; Somatic evolution in cancer; Cancer; Evolutionary biology; Carcinogenesis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002111528,0.00008843885,0.00008984345,0.00001906634,0.0001749554,0.0000142999,0.00008579491,0.00007430743,0.000001948049],"category_scores_gemma":[0.00007328083,0.00006009736,0.00005486271,0.00008381328,0.00008057179,0.000003672043,0.00003562027,0.00005041628,0.000001002766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001394579,"about_ca_system_score_gemma":0.0001226766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004249226,"about_ca_topic_score_gemma":0.0006664724,"domain_scores_codex":[0.9993274,0.0000572034,0.0001823897,0.000165868,0.0001364949,0.0001306331],"domain_scores_gemma":[0.9994472,0.00003191518,0.0001939437,0.0001753757,0.0001214025,0.00003021899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001916975,0.00008298697,0.1040212,0.00002191298,0.0001203325,8.574676e-7,0.0002208144,0.005289746,0.8642271,0.01594371,0.004557632,0.003596712],"study_design_scores_gemma":[0.001218135,0.000207042,0.9226802,0.00001632086,0.00007329512,0.000003691841,0.0002171839,0.002145692,0.06954567,0.001831992,0.001924404,0.0001363662],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882407,0.009738515,0.0007615013,0.0006419015,0.0002575327,0.0002044576,0.00005599667,0.000003589403,0.00009576801],"genre_scores_gemma":[0.9979944,0.001368053,0.00004918512,0.0000608473,0.0004204411,0.00001016161,0.00001394505,0.000006075208,0.00007686027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8186589,"threshold_uncertainty_score":0.2450699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00452657732163817,"score_gpt":0.217974105412367,"score_spread":0.2134475280907288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}