{"id":"W1492838608","doi":"10.1186/ar1336","title":"Genetics of osteoarthritis","year":2004,"lang":"en","type":"article","venue":"Arthritis Research","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Arthritis Network; School of Medicine, University of California, San Diego; Menzies Institute for Medical Research; National Cancer Institute; Arthritis Society; University of North Carolina at Chapel Hill; Genentech; National Institutes of Health; Biogen; Lupus Research Institute; Pfizer; Natural Sciences and Engineering Research Council of Canada; Dutch Arthritis Association; Oesterreichische Nationalbank; Deutsche Forschungsgemeinschaft; Nuffield Foundation; Physiotherapy Foundation of Canada; Canadian Institutes of Health Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Lupus Research Alliance; Wellcome Trust; Newcastle University; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Austrian Science Fund; Arthritis Foundation","keywords":"Heritability; Biology; Genetics; Gene; Genome-wide association study; Most recent common ancestor; Osteoarthritis; Genome; Bioinformatics; Medicine; Genotype; Single-nucleotide polymorphism; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004371391,0.0001368396,0.000337227,0.0003068777,0.0001406572,0.00002351578,0.0001207855,0.0001283693,0.0003430618],"category_scores_gemma":[0.0001282817,0.0001374556,0.000129664,0.0004979764,0.0003374126,0.00008702226,0.00009860652,0.0003153942,0.0004063007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008034568,"about_ca_system_score_gemma":0.000303024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006141399,"about_ca_topic_score_gemma":0.0001762067,"domain_scores_codex":[0.9978051,0.00007171971,0.0003329908,0.000323567,0.0008873592,0.0005792216],"domain_scores_gemma":[0.9986919,0.00006422052,0.00003773842,0.0004721009,0.0004616161,0.0002724433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002061853,0.0005125362,0.002787649,0.00005855212,0.00002795684,0.0008793266,0.0004332945,0.000004123753,0.1371361,0.01426386,0.0002317543,0.8434587],"study_design_scores_gemma":[0.02636592,0.02211771,0.004081382,0.001598208,0.00002936387,0.00115906,0.000745683,0.000002912474,0.8978884,0.02050256,0.0251796,0.0003292046],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9629719,0.01476158,0.00004131567,0.0007006661,0.0001331859,0.0007602592,0.00002814471,0.00006068288,0.02054232],"genre_scores_gemma":[0.9918154,0.00335811,0.003675995,0.00006527411,0.0001441876,0.00007081062,0.00003638264,0.00003696793,0.000796809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8431295,"threshold_uncertainty_score":0.5605278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05406184865892615,"score_gpt":0.3581516377057002,"score_spread":0.3040897890467741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}