{"id":"W1493085372","doi":"10.1007/978-3-642-60234-4_5","title":"Transgenic Plants for Therapeutic Proteins: Linking Upstream and Downstream Strategies","year":2000,"lang":"en","type":"review","venue":"Current topics in microbiology and immunology","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":133,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sembiosys Genetics (Canada)","funders":"","keywords":"Oleosin; Downstream processing; Commercialization; Biotechnology; Downstream (manufacturing); Bioproduction; Genetically modified crops; Genetically modified rice; Transgene; Biology; Engineering; Biochemistry; Business; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008564386,0.0003463679,0.0006968798,0.00009726897,0.0001000416,0.00002242217,0.0002295207,0.0007217678,0.000009562721],"category_scores_gemma":[0.000003366592,0.0002860488,0.0001353628,0.0000449302,0.0002969116,0.000004442988,0.00004561566,0.0003571725,0.000003019708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001056391,"about_ca_system_score_gemma":0.0001545298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003203747,"about_ca_topic_score_gemma":0.00004559762,"domain_scores_codex":[0.9985594,0.0001140639,0.0004108269,0.0005616064,0.00001325015,0.0003409225],"domain_scores_gemma":[0.9995472,0.00004224585,0.0001133974,0.0002570483,0.00001286218,0.00002722473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003845648,0.00007453537,0.00002571939,0.001210648,0.000188034,4.988882e-7,0.00004034927,2.848666e-7,0.003613553,0.0005023302,0.00003704083,0.9942685],"study_design_scores_gemma":[0.0005198685,0.000181797,0.00002276431,0.0007670281,0.0001236863,0.0001265064,0.00002488538,3.774236e-7,0.0002148201,0.0004162326,0.9973067,0.000295338],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005965451,0.9919026,0.000291552,0.00002800336,0.0002135699,0.001011531,0.0005278007,0.00001123007,0.00004822461],"genre_scores_gemma":[0.002254598,0.9948395,0.000112625,0.00002024973,0.000143255,0.0003657579,0.002161718,0.00002229491,0.00007999543],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9972696,"threshold_uncertainty_score":0.9999592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0338060111268045,"score_gpt":0.319615685035596,"score_spread":0.2858096739087915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}