{"id":"W1493305850","doi":"10.4049/jimmunol.184.supp.145.25","title":"Rapamycin promotes tolerance through increased expression of CD4+CD25+Foxp3+ regulatory T cells and impaired development of CD8+CD44+CD62L+ memory T cells. (145.25)","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"FOXP3; IL-2 receptor; Immune tolerance; CD8; Immunology; Transplantation; Biology; CD44; Immunosuppression; Cytotoxic T cell; Cancer research; Andrology; Antigen; Immune system; Medicine; T cell; Internal medicine; Cell; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001124317,0.0003824144,0.0002750008,0.0002753749,0.00009415029,0.000245341,0.0001054162,0.0001676495,0.001561577],"category_scores_gemma":[0.00005181304,0.0001181021,0.0002068605,0.0001019128,0.0001826297,0.0001408361,0.0001119973,0.0005034896,0.0002956167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009739576,"about_ca_system_score_gemma":0.00009044894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001710488,"about_ca_topic_score_gemma":0.0003006493,"domain_scores_codex":[0.9998928,0.00001911552,0.00001095269,0.00002118763,0.00002486538,0.00003097396],"domain_scores_gemma":[0.9998912,0.00001175521,0.00004539022,0.000008540494,0.000006977285,0.00003603644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001121068,0.00002617509,0.0001387556,0.00002417441,0.000002735017,0.00002113817,0.000004728823,0.00001872883,0.9988191,0.00001047985,0.00002330887,0.0007985191],"study_design_scores_gemma":[0.00002598747,0.002365183,0.01888363,0.0000087242,0.00002796146,0.0003934091,0.0000230886,0.0004156889,0.9763048,0.00002722505,0.00151856,0.000005792801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965265,0.001424855,0.0009156059,0.0000323339,0.00002910885,0.0000156008,0.0002111188,0.0001443761,0.0007003766],"genre_scores_gemma":[0.9965587,0.0005924706,0.0009766124,0.00004618055,0.00002387447,0.00002961568,0.0002799388,0.0000186436,0.001473895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001561577,"threshold_uncertainty_score":0.005223989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00909282135820796,"score_gpt":0.2108381629081326,"score_spread":0.2017453415499247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}