{"id":"W1493319756","doi":"10.1139/o08-130","title":"Src kinase Hck association with the WASp and mDia1 cytoskeletal regulators promotes chemoattractant-induced Hck membrane targeting and activation in neutrophilsThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.","year":2009,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Wiskott–Aldrich syndrome protein; Cell biology; Tyrosine phosphorylation; Cytoskeleton; Chemotaxis; MDia1; Actin; Actin cytoskeleton; Proto-oncogene tyrosine-protein kinase Src; Biology; Phosphorylation; Chemistry; Biochemistry; Receptor; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000757281,0.0001604058,0.0002469194,0.00003774455,0.0001249671,0.00003531221,0.00006271533,0.0002292855,0.0001091983],"category_scores_gemma":[0.0003013742,0.0001152049,0.00002446001,0.0001312291,0.0001029173,0.00002511098,0.00004236059,0.0002384046,3.670272e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002999398,"about_ca_system_score_gemma":0.00006479261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004339057,"about_ca_topic_score_gemma":0.00006782103,"domain_scores_codex":[0.9989889,0.0001069151,0.0003365682,0.0002720824,0.0001276464,0.0001678501],"domain_scores_gemma":[0.9992042,0.00005016914,0.0004036083,0.00009357075,0.0002035582,0.00004484579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008871423,0.00007118276,0.001197668,0.0002394337,0.00003294237,3.178562e-7,0.0003148583,8.959716e-7,0.9962912,0.000008012195,0.0001742123,0.001580607],"study_design_scores_gemma":[0.0006287141,0.0003893434,0.001861614,0.0001862182,0.00006086364,0.00002151328,0.0007353409,0.0002526297,0.9949781,0.00004683937,0.0006959346,0.0001429047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928312,0.002659298,0.000007278822,0.003913546,0.00002279931,0.0002237738,0.00001334844,0.000002325931,0.000326449],"genre_scores_gemma":[0.9937042,0.005673608,0.00006643729,0.0001264345,0.0001598735,0.000004953861,0.00007562371,0.000009155615,0.0001796889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003787112,"threshold_uncertainty_score":0.4697918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005841279788821811,"score_gpt":0.2181597588769276,"score_spread":0.2123184790881058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}