{"id":"W1493319756","doi":"10.1139/o08-130","title":"Src kinase Hck association with the WASp and mDia1 cytoskeletal regulators promotes chemoattractant-induced Hck membrane targeting and activation in neutrophilsThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.","year":2009,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Wiskott–Aldrich syndrome protein; Cell biology; Tyrosine phosphorylation; Cytoskeleton; Chemotaxis; MDia1; Actin; Actin cytoskeleton; Proto-oncogene tyrosine-protein kinase Src; Biology; Phosphorylation; Chemistry; Biochemistry; Receptor; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001040861,0.0002913773,0.0002381558,0.0001666081,0.0002503789,0.0003180799,0.0001462163,0.0002413605,0.002056163],"category_scores_gemma":[0.00008892162,0.0001872105,0.0002794192,0.0001322519,0.0001944025,0.0001905,0.000376581,0.0005321866,0.0007437387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004367183,"about_ca_system_score_gemma":0.0002479772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005951443,"about_ca_topic_score_gemma":0.001111196,"domain_scores_codex":[0.9997582,0.00002814997,0.00001439453,0.00004739423,0.00006421405,0.00008762902],"domain_scores_gemma":[0.9999137,0.000007088971,0.00002109862,0.000008281163,0.000009567788,0.00004024211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008207084,0.000008598159,0.0001950292,0.00002340001,0.000003400545,0.00003102686,0.000008495232,0.00001076774,0.9992725,0.00003778618,0.00005169425,0.0002752173],"study_design_scores_gemma":[0.00002370028,0.0001176454,0.03317504,0.00000993661,0.000015218,0.0003981839,0.00006321363,0.001143504,0.9612327,0.00004685254,0.003768085,0.000005925905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951465,0.002186995,0.001225232,0.0001446774,0.00005905641,0.00002045862,0.0002595606,0.00004476386,0.000912767],"genre_scores_gemma":[0.9935948,0.0008924882,0.0009631568,0.00005940492,0.00002153115,0.0000293836,0.000767022,0.00001647617,0.003655766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002056163,"threshold_uncertainty_score":0.006878495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005841279788821811,"score_gpt":0.2181597588769276,"score_spread":0.2123184790881058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}