{"id":"W1493418974","doi":"10.4049/jimmunol.166.10.5889","title":"CD44-Deficient Mice Exhibit Enhanced Hepatitis After Concanavalin A Injection: Evidence for Involvement of CD44 in Activation-Induced Cell Death","year":2001,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Liver physiology and pathology","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Apoptosis; Knockout mouse; Liver injury; Spleen; CD44; Tumor necrosis factor alpha; Hepatitis; Endocrinology; Internal medicine; Programmed cell death; Concanavalin A; Adoptive cell transfer; Immunology; Medicine; Chemistry; Biology; T cell; Cell; Receptor; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001462831,0.0007102215,0.000310085,0.0006295137,0.0001895411,0.0004539512,0.0001925149,0.000601356,0.003111708],"category_scores_gemma":[0.0001234635,0.000315578,0.000316217,0.0002224473,0.0003677596,0.0004054097,0.0002190568,0.001104096,0.0007818163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002529923,"about_ca_system_score_gemma":0.0001661292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003046336,"about_ca_topic_score_gemma":0.00041795,"domain_scores_codex":[0.9997794,0.00003233826,0.00002063114,0.00004295427,0.00006087545,0.00006384859],"domain_scores_gemma":[0.9995584,0.00002863356,0.0001997036,0.00003880643,0.00002621456,0.000148279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001547344,0.00005373649,0.000307044,0.00002156464,0.00000491744,0.0000779586,0.000007756551,0.00003293371,0.9986932,0.00006246872,0.00002724604,0.0005564807],"study_design_scores_gemma":[0.00008391016,0.0008593613,0.02426096,0.00001885169,0.00004604207,0.00127535,0.00005524611,0.002469331,0.9690294,0.0001399564,0.001751368,0.00001036778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958951,0.0005885528,0.002052562,0.0001494115,0.00002460649,0.00002380698,0.0003385492,0.0001056819,0.0008216248],"genre_scores_gemma":[0.9923154,0.0007831566,0.00216494,0.00008394967,0.00002318198,0.00005262894,0.0005447796,0.00004118635,0.003990792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003111708,"threshold_uncertainty_score":0.01040971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05020934372996584,"score_gpt":0.3066494430340094,"score_spread":0.2564400993040436,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}