{"id":"W1493418974","doi":"10.4049/jimmunol.166.10.5889","title":"CD44-Deficient Mice Exhibit Enhanced Hepatitis After Concanavalin A Injection: Evidence for Involvement of CD44 in Activation-Induced Cell Death","year":2001,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Liver physiology and pathology","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Apoptosis; Knockout mouse; Liver injury; Spleen; CD44; Tumor necrosis factor alpha; Hepatitis; Endocrinology; Internal medicine; Programmed cell death; Concanavalin A; Adoptive cell transfer; Immunology; Medicine; Chemistry; Biology; T cell; Cell; Receptor; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007110026,0.0001167501,0.0004028668,0.0001850335,0.00004812508,0.000002049862,0.0001600025,0.0001447723,0.0001101924],"category_scores_gemma":[0.0002057402,0.00008132323,0.000100554,0.0001819578,0.0001219019,0.00009912805,0.00004241172,0.000350109,0.000005679362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001340657,"about_ca_system_score_gemma":0.0002248877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003709481,"about_ca_topic_score_gemma":0.0001132244,"domain_scores_codex":[0.9986854,0.0003023339,0.0005725994,0.0001150867,0.0001125712,0.0002119779],"domain_scores_gemma":[0.9982649,0.0006600287,0.0004993201,0.0002055345,0.0003411429,0.00002905855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006827389,0.0002660807,0.01705754,0.00004762452,0.0001149545,0.00002712153,0.002894065,0.00007948426,0.9718305,0.00006330806,0.00005657958,0.0007353363],"study_design_scores_gemma":[0.004419611,0.007285721,0.2952645,0.0005476988,0.0002241108,0.0006352749,0.001158873,0.00003572636,0.6893308,0.0007775833,0.0001869984,0.0001331418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956704,0.001408563,0.001236703,0.0009115545,0.0003175067,0.000346089,0.000001973371,0.000004224485,0.0001029934],"genre_scores_gemma":[0.9976916,0.001069544,0.0003449937,0.0006340476,0.0001076803,0.00002269365,0.000002148919,0.00000928211,0.0001180584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2824998,"threshold_uncertainty_score":0.3316265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05020934372996584,"score_gpt":0.3066494430340094,"score_spread":0.2564400993040436,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}