{"id":"W1493459286","doi":"10.1038/cti.2015.8","title":"A GMCSF and IL7 fusion cytokine leads to functional thymic‐dependent T‐cell regeneration in age‐associated immune deficiency","year":2015,"lang":"en","type":"article","venue":"Clinical & Translational Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Institute for Research in Immunology and Cancer","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; Georgia Cancer Coalition","keywords":"Biology; Lymphopoiesis; CD8; Immunology; T cell; Thymic involution; Immune system; IL-2 receptor; Cytokine; Progenitor cell; Cell biology; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001079107,0.0003289243,0.000242816,0.0002245426,0.00008917765,0.0001278525,0.0002106925,0.0003265348,0.0007937907],"category_scores_gemma":[0.00009109927,0.00009498833,0.0002356098,0.00009737543,0.0001898177,0.0001188744,0.0001634338,0.0004211365,0.0002840093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001537212,"about_ca_system_score_gemma":0.0001398693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002036282,"about_ca_topic_score_gemma":0.000220048,"domain_scores_codex":[0.9999006,0.00001734685,0.00001404269,0.00001820791,0.00002901136,0.00002083374],"domain_scores_gemma":[0.999894,0.00001879234,0.00003003211,0.000007912507,0.000007631637,0.00004156689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001655029,0.00007041129,0.0001091396,0.00003024862,0.000003827021,0.0001396138,0.000009502724,0.00007280229,0.9980168,0.00006513359,0.00003417685,0.00128292],"study_design_scores_gemma":[0.00007337661,0.001653894,0.002762396,0.000008919515,0.00002662662,0.001001217,0.000018381,0.001207479,0.9905964,0.00006246563,0.002583726,0.000005261335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970582,0.0007329397,0.001115262,0.00004451,0.00002051407,0.00003231791,0.0002411823,0.00007507571,0.0006799951],"genre_scores_gemma":[0.9945722,0.0006536343,0.001861145,0.00004748701,0.00001294988,0.00004196949,0.000645823,0.000022394,0.00214246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007937907,"threshold_uncertainty_score":0.002655447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04968244531826236,"score_gpt":0.2939424062470161,"score_spread":0.2442599609287538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}